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What are 3 risk factors for males that can affect fertility? 

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Open accessJournal Article
01 Aug 1982-Hospital Practice
21 Citations
Male fertility decline is more subtle, but a man’s age affect the chances of his (female) partner conceiving, and increases the risk of miscarriage, and the child’s risk of mental health and developmental disorders.
Book ChapterDOI
01 Jan 2014
5 Citations
A variety of factors may influence fertility in males, including genetic abnormalities, diseases or environmental agents and, for humans, also occupational hazards and lifestyle.
The effects of adult lifestyle--primarily smoking and diet in women, and sedentary habits generally--are important factors affecting the fertility of men and women, and can also impact the fertility of their children.
BACKGROUND Lifestyle has been shown to affect fertility in both males and females, with compelling evidence that smoking and being under or overweight impairs natural and assisted fertility, and other factors such as stress and caffeine have also been implicated.
Although quality of evidence should be ameliorated, it emerges that environmental factors can influence male fertility.
At the same time, immunological reactions occurring via cytokines appear to be both beneficial and/or risk factors for male fertility.
The major lifestyle factors discussed in the present review are amongst the multiple potential risk factors that could impair male fertility.
Journal ArticleDOI
Adam F. Stewart, Edward D. Kim 
01 Sep 2011-Urology
93 Citations
Most evidence suggests trends that increased paternal age has negative effects on fertility and some genetic risk for offspring, but the age at which the risk develops and the magnitude of risk are poorly defined.
This study points toward a change in fertility risk factors at menopause
These factors also may be involved in the regulation of sperm cell functions and thus may affect male fertility.

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What are the factors that affect male infertility?5 answersMale infertility is influenced by various factors. Lifestyle choices such as smoking, alcohol intake, obesity, and exposure to environmental contaminants like pesticides and heavy metals can contribute to male infertility. Oxidative stress, caused by the overproduction of reactive oxygen species (ROS), is a major factor affecting sperm quality and quantity. Genetic factors also play a role in male infertility, with abnormalities in genes affecting sperm function and production. Other factors include semen abnormalities, varicocele, testis disorders, heat exposure, anabolic steroid use, vascular abnormalities, anti-spermatogenesis factors, certain medications, and chronic diseases. Additionally, chromosomal abnormalities and genetic defects can impact spermatogenesis and lead to male infertility. Understanding these factors is crucial for developing strategies to prevent and manage male infertility.
What are the most common causes of male infertility?4 answersMale infertility can be caused by various factors including genitourinary tract infections, leukocytospermia, bacteriospermia, endocrine disruption, exposure to toxins, lifestyle, genetic and epigenetic modifications, varicocele, inflammatory diseases of the reproductive system, hormonal disorders, cryptorchidism, chromosomal abnormalities, chromosomal rearrangements, Y chromosome microdeletions, single-gene mutations, gene polymorphisms or copy number variations, mitochondrial microdeletions, and other genetic deletions or mutations. These factors can contribute to impaired spermatogenesis, altered seminal parameters, and abnormal sperm function, leading to male infertility. The exact cause of male infertility can be difficult to determine in many cases, and a significant proportion of male infertility cases remain idiopathic. Genetic aberrations play a significant role in male infertility, and the presence of epigenetic alterations has also been implicated in the pathogenesis of male infertility. Proper diagnosis and evaluation of these factors are essential for the management and treatment of male infertility.
Is alcohol consumption harmful to male fertility?5 answersAlcohol consumption can have negative effects on male fertility. Studies have shown that chronic alcohol intake can lead to abnormalities in spermatogenesis and various parts of the reproductive tract, as well as decreased fertilization rates in murine oocytes. Additionally, alcohol consumption has been associated with negative effects on ejaculate parameters, including hypogonadism and altered gonadotropin levels. However, the association between alcohol intake and semen parameters in primary infertility is unclear. In men with secondary infertility, heavy alcohol consumption has been linked to smaller testis volumes and lower sperm concentrations, increasing the risk of abnormal sperm concentrations. It is recommended that men seeking fertility treatment for secondary infertility avoid heavy alcohol consumption. Occasional alcohol consumption, within recommended limits, may not significantly affect fertility but can lead to the accumulation of macrocephalic sperm potentially containing damaged DNA.
What are the different factors that affect male fertility?4 answersMale fertility can be affected by various factors. One important factor is oxidative stress, which is caused by the overproduction of free radicals and can impact sperm quality and quantity. Mitochondrial irregularities can also lead to compromised fertility by affecting sperm motility and signaling pathways. Inflammation and the production of cytokines triggered by oxidative stress can arrest sperm function. Seminal plasma proteomes, which interact with oxidative stress, can also influence male fertility. Occupational, environmental, and lifestyle factors such as exposure to pollutants, smoking, and poor nutrition can also play a role in male infertility. Genetic factors and viral infections, such as HPV, can also contribute to male infertility. Overall, understanding these factors is crucial for improving our understanding of male infertility and developing strategies to prevent it.
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