What are factors in diet that can decrease risk of cancer?
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63 Citations | These results thus suggest that a low-risk diet for cancer entails increasing vegetables and fruit, reducing meat, but also refined carbohydrate consumption. |
| Factors which decrease the risk of cancer are physical activity, fruits and vegetables, dietary fiber, dairy products and breastfeeding. | |
| It is thought that a diet containing defensive micronutrients as well as carcinogens and mutagens may adapt the risk of cancer development, particularly in genetically susceptible individuals. | |
65 Citations | Diet-gene interactions likely contribute considerably to the observed inter-individual variations in cancer risk in response to exposures to the nutritional factors that have the potential to promote or protect against cancer. |
| Epidemiology studies indicate that diet or specific dietary components can reduce the risk for cancer, cardiovascular disease and diabetes. | |
20 Citations | RESULTS: Diet and cancer studies show that, generally, vegetables and fruits, dietary fiber, and certain nutrients seem to be protective against cancer, whereas fat, excessive calories, and alcohol seem to increase cancer risk. |
65 Citations | Increased knowledge in this area will allow a more refined approach to reducing risk for cancer, with diet interventions targeted toward individuals and subgroups that are genetically susceptible and responsive to the effects of nutritional factors. |
128 Citations | However, the conclusion that diet is linked directly to epigenetic alterations and that these epigenetic alterations directly increase or decrease the risk of human cancer is much less certain. |
Open access•Journal Article 11 Citations | Several lines of evidence indicate that diet and nutrition can contribute to human cancer risk, because of carcinogenesis process6-10. |
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How can diet affect gene expression?4 answersDiet can significantly impact gene expression in various tissues. For instance, a study on cancer cachexia in mice revealed that a linoleic acid-rich diet induced substantial transcriptome changes in the liver and adipose tissues, potentially enhancing insulin sensitivity through metabolic alterations. In another study on bumble bees, consumption of sunflower pollen led to upregulation of immune and detoxification transcripts, influencing the response to gut pathogens. Furthermore, a human study demonstrated that supplementation with a mixed apple and bergamot juice altered gene expression related to oxidative and inflammatory processes, potentially reducing the risk of chronic diseases. These findings collectively highlight the intricate relationship between diet and gene expression, emphasizing the importance of dietary components in modulating physiological responses at the genetic level.
What diet should cancer patients have?4 answersCancer patients should follow a healthy diet that includes adequate caloric and protein intake, correction of vitamin and mineral deficiencies, and consideration of fish oil or long-chain N-3 fatty acid supplements. The American Institute for Cancer Research (AICR) recommends preserving a healthy body weight, engaging in physical activity, eating a diet high in fiber and soy, and limiting the consumption of fats, particularly saturated fatty acids. Various dietary interventions have shown promise in reducing cancer growth, progression, and treatment toxicity, such as intermittent fasting, ketogenic diets, and caloric restriction. The Mediterranean diet, due to its antioxidant and anti-inflammatory properties, is also considered a protective factor against cancer. However, it is important to personalize the diet based on the patient, therapeutic regimen, and cancer type, as the best diet is the one the patient is willing and able to follow. Further studies are needed to determine the most effective diet interventions for improving cancer prognosis and patient survival.
What foods can help reverse tumour growth?4 answersConsumption of bioactive compounds present in foods such as α-carotene, β-carotene, β-cryptoxanthin, lycopene, omega-3 fatty acids, and fiber has been shown to help reverse tumor growth. Additionally, the administration of a juice containing essential nutrients, marine omega-3 fatty acids, polyphenols, vitamin D3, essential amino acids, and dietary fiber, has been found to reduce tumor weight. Caloric restriction (CR) has also been shown to inhibit tumor growth by lowering lipid levels in the plasma and tumors, impairing tumor stearoyl-CoA desaturase (SCD) activity, and causing an imbalance between unsaturated and saturated fatty acids. Furthermore, increasing consumption of whole grains, vegetables, fruits, and pulses such as beans has been associated with a decreased risk of cancer and the ability to alter tumor behavior.
How can a bad diet increase chances of cancer?1 answersA bad diet can increase the chances of cancer through various mechanisms. Unhealthy diets that are high in sodium, red/processed meat, trans fat, and sugar-sweetened beverages, while low in whole grains, fruits, vegetables, and fiber, have been linked to an increased risk of cancer. Specific dietary factors such as overnutrition/obesity, alcohol, red and processed meat, and salt have strong associations with an increased risk of various cancers. On the other hand, diets rich in fruits, vegetables, whole grains, fiber, dairy, calcium, and coffee have been found to have strong links to a decreased risk of cancer. Chronic inflammation, which is modulated by diet, is also a key factor in cancer development. Proinflammatory dietary patterns, such as the Western-style diet high in ultraprocessed foods, animal fat, sugar, and food additives, can lead to chronic inflammation and an increased risk of cancer. Overall, a bad diet can contribute to cancer development by promoting inflammation, obesity, and other detrimental effects on the body.
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