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What are the challenges in controlling dengue? 

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Controlling dengue poses several challenges. The complexity of factors involved in its spread makes it difficult to eradicate. Factors such as climate change, rapid urbanization, and weak surveillance systems contribute to the increasing frequency of epidemics and severe dengue disease. Additionally, the lack of specific antiviral therapies and the reliance on mosquito vector control as the main strategy further complicate control efforts. The use of mathematical models to understand the behavior of dengue and assess the impact of control methods has shown that mechanical control, insecticide control, and larvicide control can all have a positive impact on reducing dengue cases. However, there is a need for better integration of entomological and disease surveillance systems, as well as improved reporting and surveillance strategies to accurately capture the true burden of the disease. Furthermore, sustaining preventive activities among communities is a challenge, as they often only take place during outbreaks.

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The paper discusses the challenges in controlling dengue, including the lack of integration between entomological and disease surveillance systems, under-reporting of cases, and the need for improved targeting of interventions.
The paper does not explicitly mention the challenges in controlling dengue.
The challenges in controlling dengue include weak surveillance systems, unplanned rapid urbanization, and limited resources for vector control and prevention strategies.
The challenges in controlling dengue include viral structural heterogeneity, autoimmune complications, genetic variants, antigen competition, and host-susceptibility determinants.

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