scispace - formally typeset
Search or ask a question

What are the functions of myelin? 


Best insight from top research papers

Myelin has multiple functions in the nervous system. It acts as an electrical insulator around axons, ensuring rapid propagation of nerve impulses . Myelin also provides trophic support along the axon and organizes the unmyelinated nodes of Ranvier . Additionally, myelin interacts with axons and regulates the nervous system actively . It dynamically changes axons and divides them into distinct functional domains, such as the node of Ranvier, paranode, juxtaparanode, and internode . Myelin also contributes to memory consolidation and recall by increasing functional coupling between neuronal ensembles encoding experience . Furthermore, myelin plays a role in axonal growth regulation and maintenance . It is crucial for CNS development and is involved in cognitive and behavioral effects associated with disorders and factors altering myelination .

Answers from top 5 papers

More filters
Papers (5)Insight
The paper discusses the functions of myelin in axonal growth regulation and maintenance.
The paper discusses the role of myelin in memory and suggests that myelin has a dynamic role in regulating neuronal circuits during learning and memory. However, it does not explicitly mention the specific functions of myelin.
Open accessJournal ArticleDOI
R. Douglas Fields, Olena Bukalo 
39 Citations
The paper is about the role of myelin in memory consolidation and recall. It does not explicitly mention the functions of myelin outside of this context.
The functions of myelin include electrical insulation of axons for rapid nerve impulse propagation, trophic support along the axon, organization of unmyelinated nodes of Ranvier, and its relationship to neurologic diseases like multiple sclerosis.
Open accessJournal ArticleDOI
01 Aug 2022
Myelin functions as an insulator for the rapid and efficient propagation of action potentials by saltatory conduction. It also interacts with axons and regulates the nervous system actively.

Related Questions

What are the main functions of skin?5 answersThe skin serves multiple crucial functions essential for human survival. It acts as a protective barrier against physical, chemical, and biological agents, including UV radiation. Additionally, the skin regulates body hydration, facilitates sensory perception, aids in thermoregulation, synthesizes vitamin D, and plays a role in immune surveillance. Furthermore, the skin is involved in excreting waste through sweat glands, enabling socio-sexual communication, and supporting reproduction through hormone and pheromone release. Skin also plays a critical role in wound healing, with phases like coagulation, inflammation, fibroplasia, and remodeling, ultimately leading to re-epithelialization or scarring. Overall, the skin's functions extend beyond protection, encompassing sensory, regulatory, and reparative roles crucial for overall well-being.
What is the specific function of microglia during the process of demyelination?5 answersMicroglia play multiple roles during demyelination. They respond to demyelination by generating a robust microglial response, which includes the activation of specific microglial subpopulations. Microglia are involved in the clearance of dead oligodendrocytes, preferentially phagocytosing lytic carcasses. They also contribute to the clearance of myelin debris, which is essential for remyelination. Microglia are responsible for the phagocytosis of myelin debris and have impaired phagocytic capacity in the absence of aryl hydrocarbon receptor (AhR). Additionally, microglia are important for maintaining blood-brain barrier (BBB) integrity during demyelination. Microglial depletion ameliorates BBB impairment in experimental autoimmune encephalomyelitis (EAE). Overall, microglia have a crucial function in responding to demyelination, clearing cellular debris, and maintaining BBB integrity.
What are the functions of serotonin?5 answersSerotonin is a neurotransmitter that plays a significant role in plant growth and stress response, including root, shoot, flowering, morphogenesis, and adaptability responses to environmental signals. It also has effects on adhesion and cytoskeletal remodeling, which are important for neuronal processes and psychiatric illnesses. In the central nervous system, serotonin regulates mood, behavior, and systemic energy balance by decreasing appetite. Additionally, serotonin acts as a guidance cue in shaping neuronal circuit formation during development. Deficits in the serotonergic system can lead to various pathological conditions, including depression, schizophrenia, mood disorders, and autism.
What is the function of the optic nerve?5 answersThe optic nerve is responsible for transmitting visual information from the retina to various structures in the central nervous system (CNS). It carries visual information from the neurosensory retina to the occipital cortex. The optic nerve is an extension of the brain parenchyma and transmits electrical impulses that are processed into visual information. It maintains a strict visuotopic representation at all intermediate relay stations and plays a crucial role in the entire visual pathway. The optic nerve can be directly visualized through the window of the eye, allowing for the assessment of its integrity and the area of origin of its nerve fibers.
How to perform cell separation and myelination?5 answersTo perform cell separation and myelination, a cell culturing platform can be used to model myelination in vitro. Oligodendrocyte progenitor cells can be generated from human pluripotent stem cells and isolated for myelination studies. Dissociated cerebral neurons can be cultivated using a rapid attachment method, leading to fiber growth, synaptogenesis, and myelin formation. Myelinating oligodendrocytes can be generated from mouse embryonic stem cells, and a myelin formation assay can be established using embryonic stem cell-derived neurons in microfluidic devices. A microfluidic-based compartmentalized culture system can be used to achieve segregation of neuron and oligodendrocyte cell bodies while allowing the formation of myelin sheaths. Electrical stimulation can be applied to increase myelination levels in this system.
What are the main functions of growth cones?5 answersGrowth cones are specialized structures at the tips of developing axons that play a critical role in axon growth, guidance, and pathfinding. They are important during both neuronal development and adult regeneration. Growth cones are responsible for extending neuronal processes, such as axons, and are essential for nerve growth and accurate synaptogenesis. They are highly motile and rely on spatially controlled endocytosis and exocytosis for their motility. Growth cones interpret and navigate through the complex landscape and guidance cues of the nervous system. They also play a role in axonal outgrowth and turning events, facilitated by microtubules and microtubule plus-end tracking proteins. Additionally, growth cones recycle cell adhesion molecules to polarize growth cone adhesiveness along the axis of migration direction.

See what other people are reading

Can a deep learning model with multilingual sentiment analysis be used to forecast stock market prices?
4 answers
Yes, deep learning models with sentiment analysis capabilities have shown promise in forecasting stock market prices. Research has explored the combination of deep learning techniques like LSTM and BERT for stock price prediction. These models leverage historical stock data and sentiment analysis of sources like Twitter posts to enhance accuracy and robustness in predicting market movements. Incorporating sentiment from various sources, including multilingual data, can provide valuable insights into investor behavior and market trends, potentially improving prediction outcomes. The use of advanced deep learning models trained on multilingual sentiment data can offer a comprehensive understanding of market sentiment across different languages, contributing to more accurate stock price forecasts.
How have the methods of perfume fragrance extraction evolved over time?
5 answers
Perfume fragrance extraction methods have evolved significantly over time. Initially relying on natural ingredients, modern techniques now focus on sustainable extraction processes to preserve biodiversity. Traditional methods like Hydrodistillation and Steam Distillation are being enhanced with innovative technologies such as Solvent-Free Microwave Extraction and Microwave Hydrodiffusion and Gravity, offering improved efficiency and extract quality. Moreover, advancements in analytical tools like Gas Chromatography-Mass Spectrometry have revolutionized the analysis of fragrance compounds, ensuring a more comprehensive understanding of the volatile components in perfumes. Additionally, the development of fragrance dispensers with sophisticated mechanisms like impellers and fragrant material cartridges showcases a blend of traditional and modern approaches in dispensing fragrances. These advancements collectively reflect a shift towards greener, more efficient, and sustainable practices in the perfume industry.
How does the level of auditor independence affect the quality of audits conducted in Vietnam's commercial banks?
4 answers
The level of auditor independence significantly impacts the quality of audits in Vietnam's commercial banks.The research findings suggest that factors such as political hegemony, auditor tenure, and relationships with auditees can negatively affect auditor independence, while independence itself positively influences audit quality.Moreover, the study highlights that auditor competence and ethics also play crucial roles in enhancing audit quality, with ethics acting as a moderating variable in the relationship between independence and audit quality.Additionally, recent audit reforms in Vietnam have revealed concerns about low-quality audits, non-compliance with standards, and independence issues, particularly among smaller audit practitioners, emphasizing the importance of maintaining and strengthening auditor independence for ensuring high-quality audits in commercial banks.
How does compassion contribute to the process of peacebuilding and conflict resolution?
4 answers
Compassion plays a crucial role in peacebuilding and conflict resolution by fostering benevolent intersubjectivity, promoting cultures of critical compassion in education, and serving as a conflict-proof commitment to transforming conflicts into enduring peace. Through compassion, individuals can reduce stress, resolve conflicts, and cultivate conflict-proof well-being. Compassion interventions, rooted in specific parental brain mechanisms, can help in reducing stress and mediating conflicts effectively. By practicing compassion towards others, including friends and foes alike, individuals can suspend identity-based biases, enhance attunements to counterparts in conflicts, and ultimately contribute to peaceful resolutions. Overall, compassion acts as a powerful tool in building long-term, responsive, and reflexive cultures of compassion in education and beyond, fostering enduring peace and prosperity.
How does the technology behind holograms affect the perception of depth and distance?
4 answers
The technology behind holograms significantly impacts the perception of depth and distance in various applications. By utilizing innovative methods such as volume representation and improved ray tracing algorithms, metasurfaces with dielectric nanobrick arrays, and hologram communication systems, holographic displays can provide enhanced depth precision, realistic 3D effects, and improved user experiences. These advancements enable the generation of accurate depth cues, manipulation of incident beams, and exploration of affect and social presence in holographic communication. Additionally, holographic visualization technologies offer better depth perception for multidimensional structured scientific and engineering data, allowing for immersive investigations, interactive manipulations, and enhanced understanding of complex information. Overall, holographic technologies play a crucial role in revolutionizing depth perception and distance visualization across various fields.
Double strand break choice
5 answers
DNA double-strand breaks (DSBs) are repaired by either non-homologous end-joining (NHEJ) or homologous recombination (HR) pathways, with repair pathway choice being influenced by various factors. NHEJ is favored when DNA ends are protected against resection, promoting repair throughout the cell cycle. Factors like 53BP1 and its cofactors play crucial roles in inhibiting long-range end resection, thus promoting NHEJ. In contrast, HR, which mainly occurs during the S/G2 phase, requires DNA end processing for faithful repair. The choice between NHEJ and HR is critical for maintaining genome integrity and cell survival, with improper pathway selection potentially leading to genomic instability and diseases like cancer. Understanding the mechanisms that govern repair pathway choice is essential for developing effective strategies to preserve genome integrity and combat diseases associated with faulty DNA repair pathways.
How do researchers address the complexity and interpretability of AI/ML models in the context of sports science?
4 answers
Researchers address the complexity and interpretability of AI/ML models in sports science by employing Explainable Artificial Intelligence (XAI) approaches. These approaches aim to provide high-quality, interpretable explanations for model predictions in sports, especially in scenarios like predicting match outcomes. Techniques such as Boolean Rule Column Generation (BRCG), Logistic Regression (LogReg), Support Vector Machine (SVM), and Deep Neural Network (DNN) are utilized to enhance interpretability while maintaining predictive performance. Additionally, the use of methods like ProtoDash and SHAP helps in constructing post-hoc explanations for each data instance, ensuring the transparency and understandability of the model's predictions. This focus on interpretability is crucial for gaining insights into the reasoning behind AI/ML model predictions in sports science applications.
What are the potential benefits of using oregano and lemongrass as an alternative to commercial lotions?
4 answers
Using oregano and lemongrass as alternatives to commercial lotions can offer various benefits. Oregano and lemongrass contain natural chemicals that have larvicidal properties, potentially aiding in mosquito control. Additionally, a study suggests that a blend of oregano, thyme, and lemongrass essential oils can inhibit and kill foodborne pathogens, providing a natural and green alternative for safer food production. Furthermore, oregano supplementation has shown transcriptional effects that could alter gene expression related to cancer susceptibility and microbiota-gut-brain axis signaling, highlighting potential health benefits. Moreover, lemongrass and oregano essential oils exhibit antibacterial activity, with lemongrass oil showing synergistic interactions with antibiotics against antibiotic-resistant bacterial infections. Overall, the natural properties of oregano and lemongrass make them promising alternatives with various potential benefits for health and environmental purposes.
What are the various industrial applications of molybdenum oxides?
4 answers
Molybdenum oxides (MoOx) find diverse industrial applications due to their unique properties. They are utilized in alloy and catalyst applications, electrochemical capacitors, display devices, sensors, smart windows, lubricants, battery electrodes, and as SERS substrates for surface-enhanced Raman scattering (SERS) spectroscopy. Additionally, MoOx thin films grown on nanocellulose exhibit high transparency and flexibility, making them suitable for flexible electronics, including bendable displays and solar energy systems. Furthermore, MoOx nanoparticles are employed in various fields such as energy storage, photodetectors, thermoelectric devices, solar cells, photo-thermal therapies, and gas sensors, showcasing their versatility and wide-ranging industrial applications.
What is the current state of research on the use of NIRS for analyzing amylose content in liquids food?
5 answers
Current research on NIRS for analyzing amylose content in liquid food is advancing. Studies have shown that NIRS can accurately predict amylose content in yam flour. Additionally, NIRS has been successfully utilized to identify sugar (sucrose) levels in everyday drinks with high accuracy and robustness. The technique's widespread use in various industries, including food and beverages, highlights its potential for reliable and non-destructive analysis. Moreover, NIRS has been employed in studying wild rodents to determine food ingredients in their diet and assess food quality, suggesting broader applications in ecological research and practical management. Efforts are being made to implement NIRS at an industrial scale for real-time monitoring and control in food processing, emphasizing the need for further research and industry collaboration.
What are the fields that have the application of feature selection?
5 answers
Feature selection is a crucial technique applied in various fields such as bioinformatics, text classification, big data analytics, medical systems, and artificial intelligence. In bioinformatics, feature selection methods like the MMPSO algorithm aid in identifying gene signatures for distinguishing normal and tumor samples. Text classification benefits from feature selection algorithms like CHI, which enhance classification accuracy by eliminating irrelevant features. The big data domain extensively utilizes feature selection to extract informative features from high-dimensional datasets. Moreover, feature selection plays a significant role in medical applications, enabling the identification of key features related to diseases and enhancing the understanding of medical data. In the realm of artificial intelligence and pattern recognition, feature selection techniques contribute to reducing computational costs, improving classifier accuracy, and creating more efficient models.