Answers from top 8 papers
19 Apr 1977-Biochimica et Biophysica Acta
|Saccharomyces cerevisiae -136ts (Hutchison, H. T., Hartwell, L. H.|
|Unlike the other MYST family members in Saccharomyces cerevisiae this gene is essential for growth.|
|These data suggest a role for CKII in ion homeostasis in S. cerevisiae.|
03 Nov 1997-Journal of Cell Biology
|Saccharomyces cerevisiae may prove a suitable model to trace the roots of apoptosis.|
01 Mar 2015-Applied and Environmental Microbiology
|These findings will be useful for understanding the biological function of S. cerevisiae Pho13 and the HAD superfamily enzymes and for developing S. cerevisiae strains with industrially attractive phenotypes.|
01 Mar 2014-Fems Yeast Research
|This review also highlights that, despite the fact that most frontier research and technological developments are often focussed primarily on S. cerevisiae, non-Saccharomyces research can benefit from the techniques and knowledge developed by research on the former.|
01 Apr 2000-Genome Research
|Our results also indicate the loss of specific genes from S. cerevisiae.|
01 Oct 1989-Cellular Signalling
|These unique features of Saccharomyces cerevisiae, together with rapidly evolving techniques of molecular biology, have made it a successful model organism for the study of numerous questions.|
Is Anti-Saccharomyces cerevisiae Antibodies a useful biomarker for ulcerative colitis?5 answersAnti-Saccharomyces cerevisiae antibodies (ASCA) have been investigated as a potential biomarker for ulcerative colitis (UC). Several studies have explored the diagnostic value of ASCA in differentiating UC from other chronic inflammatory bowel diseases. One study found that the levels of ASCA-IgG were significantly higher in UC patients compared to non-UC controls and healthy controls. Another meta-analysis revealed a strong association between ASCA and gastrointestinal BD (GIBD), a subtype of Behcet's disease, suggesting a potential role of ASCA in the pathogenesis of gastrointestinal involvement. Additionally, ASCA has been studied as a prognostic marker in children with CD, showing that ASCA IgG-positive patients had a significantly lower relapse rate when treated with biologics. However, it is important to note that the diagnostic and prognostic significance of ASCA in UC may vary depending on the specific context and patient population.
What is saccharomyces cerevisiae in alcoholic fermentation?5 answersSaccharomyces cerevisiae is a yeast used in the winemaking industry. It has a natural preference for consuming glucose over fructose during alcoholic fermentation, which can lead to stuck or sluggish fermentations. Ethanol accumulation in the fermentation broth can also inhibit fermentation. Researchers have conducted studies to improve the fermentative abilities of S. cerevisiae strains through adaptive laboratory evolution. One study found that an evolved population of S. cerevisiae was able to ferment a high concentration of glucose and fructose to dryness in a shorter time compared to the parental strain. Another study focused on developing S. cerevisiae strains that are resistant to fermentation inhibitors, high temperature, and ethanol. These resistant strains have potential applications in ethanol fermentation. Additionally, there have been inventions related to the use of S. cerevisiae accelerants in yeast culture and alcoholic fermentation processes, which can improve yeast quantity, germination rate, and reduce residual sugars in fermented mash. Another invention highlights the application of S. cerevisiae in wine brewing, where it can produce high levels of ethyl alcohol and various volatile substances and flavor compounds. Lastly, there is an invention related to a specific strain of S. cerevisiae that has increased ethanol yield and resistance to multiple stresses in high-temperature and high-concentration mash fermentation.
How does Saccharomyces cerevisiae not produce ethanol?3 answersSaccharomyces cerevisiae is a yeast that is capable of producing ethanol. In fact, it is a well-established organism for bioethanol production. The production of ethanol by S. cerevisiae is a result of the fermentation process, where the yeast cells convert sugars into ethanol and carbon dioxide. However, the production of ethanol by S. cerevisiae can be influenced by various factors, including stress conditions and inhibitors that can hamper its efficacy for commercial bioethanol production. To overcome these challenges, yeast cells adopt different signal transduction pathways, and genetic modifications can be made to engineer yeast strains that are more efficient in producing bioethanol. Therefore, S. cerevisiae does produce ethanol, but its production can be optimized through genetic modifications and the use of different carbon feedstocks.
What causes Saccharomyces cerevisiae to not produce ethanol?5 answersSaccharomyces cerevisiae does not produce ethanol due to various factors. One of the factors is the lack of alcohol-tolerance and thermo-tolerance characteristics in the yeast strain. These characteristics are required for the efficient production of ethanol. Additionally, the stress imposed by ethanol can be a limiting factor for ethanol production in S. cerevisiae. The toxicity of high ethanol concentrations can affect the growth and viability of the yeast cells. However, genetic modifications and overexpression of certain genes, such as TRP1 and MSN2, can increase the tolerance of S. cerevisiae to ethanol. Understanding the role of specific genes, pathways, and cellular processes, such as longevity, peroxisomal, energy, and lipid metabolisms, can help improve ethanol tolerance in S. cerevisiae.
Can dogs have Saccharomyces cerevisiae?4 answers
Is Saccharomyces cerevisiae Vitamin k2?1 answers
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How can stochastic modeling be used to model and simulate Escherichia coli?
4 answersStochastic modeling is used to simulate and model Escherichia coli in various contexts. In the study by Baptista and Ribeiro, stochastic models were proposed to integrate noise from cell division and gene expression to mimic the dynamics of RNA and protein numbers in E. coli. Kahramanoğulları et al. extended their analysis by using stochastic simulations to observe noise due to small numbers of molecules and quantify information flow in the biochemical system. Campillo et al. developed stochastic models at different scales, including a stochastic jump model and approximate simulation methods, to represent the AM2b model in E. coli. Padmakumar discussed the use of modeling and simulation to optimize growth and control strategies in bioprocesses involving E. coli. These studies demonstrate the application of stochastic modeling in understanding and predicting the behavior of E. coli in different contexts.Why is stochastic modeling required for modeling and simulation of Escherichia coli?
5 answersStochastic modeling is required for modeling and simulation of Escherichia coli because it allows for the characterization of in vivo dynamics of RNA production at the single event level. This is important for understanding the transcription dynamics of E. coli promoters and designing synthetic promoters with desired RNA production kinetics. Stochastic modeling also plays a role in simulating the activity of glutamine synthetase, a key component of nitrogen metabolism in E. coli. Additionally, stochastic modeling techniques are used in computational biology to account for fluctuations and stochasticity in biological systems, such as intracellular chemical reactions and bacterial chemotaxis. Overall, stochastic modeling provides a more accurate representation of the complex and dynamic behavior of Escherichia coli, allowing for better predictions and understanding of its biological processes.How connect Scspace with zotero?
4 answersZotero is a free and open source reference management software that allows users to collect, manage, store, and cite resources in a single location. It can be used to control bibliographic data and store various research materials such as PDF files, websites, blogs, and videos. Zotero automatically imports citation information from different sources, including nonsubscription, newspaper, and commercial websites, as well as web-based databases like PubMed and MedlinePlus. It offers a wide range of note-taking options and supports multiple citation styles. Users can also integrate Zotero with Microsoft Word using a plug-in. Although Zotero does not have on-demand customer support, its website provides extensive information for users. Overall, Zotero is a platform-independent program that can be accessed anywhere with an internet connection. However, there is no direct mention of connecting scSpace with Zotero in the provided abstracts.What did Vanowski inject into the healthy plants?
5 answersVanowski did not inject anything into the healthy plants.67.What are the benefits of holding the 5’ and the 3’ ends of the mRNA in close proximity?
3 answersThe benefits of holding the 5' and 3' ends of mRNA in close proximity include regulation of translation initiation and mRNA decay, as well as facilitation of protein complex formation that bridges the mRNA ends. The close distance between the ends is a sequence-independent property of most RNAs, and only low-complexity sequences without guanosines exhibit end-to-end distances expected for random coil conformation. The proximity of mRNA ends allows for the binding of translation factors that bridge the mRNA 5' and 3' untranslated regions (UTRs), enhancing translation initiation. Additionally, the close proximity of the ends may mediate the coupling of 3' deadenylation to 5' end mRNA decay. Overall, the inherent compactness of mRNA and the proximity of its ends have important biological implications in regulating mRNA translation and stability.What are the effects of AREs on RNA turnover?
3 answersAU-rich elements (AREs) have been shown to modulate mRNA half-life and can modify mRNA abundance in trypanosomes. These regulatory processes are specific for different developmental stages and allow trypanosomes to adapt to variable environmental conditions.How does the flavivirus methyltransferase differ to host methyltransferases?
3 answersThe flavivirus methyltransferase (MTase) differs from host methyltransferases in several ways. Firstly, the flavivirus MTase is responsible for the methylation of the 5' cap structure of the viral RNA genome, specifically at the N7 and 2'-O positions. This cap methylation is essential for viral replication and evasion of host innate immunity. In contrast, host methyltransferases do not methylate the viral RNA cap structure. Secondly, the flavivirus MTase has been shown to have a novel internal RNA methylation activity, specifically methylating adenosine residues at the 2'-OH position. This internal methylation has been found to attenuate viral RNA translation and replication. Host methyltransferases do not possess this internal methylation activity. Overall, the flavivirus MTase has unique enzymatic activities that are specific to viral RNA methylation, distinguishing it from host methyltransferases.What is the background of HIV?
5 answersThe background of HIV is that it is a public health concern that affects men, women, and children. The virus not only infects individuals but also affects society as a whole. It leads to a restructuring of daily life and social spaces for those infected. HIV is often depicted as a terrible monster capable of decimating entire societies. HIV is a retrovirus that stores its genetic information in the form of RNA. It belongs to the family of retroviruses and is able to reverse the normal flow of genetic information by copying its RNA genome into DNA using reverse transcriptase. The emergence and rapid spread of HIV provides an opportunity to study the evolution and maintenance of virulence in a major human pathogen. The prevalence of HIV is an indicator of uneven or dysfunctional social development, with the highest prevalence found in poor societies, societies in turmoil, and among the marginalized.How does the presence of pollutants affect the overall rate of biodegradation?
5 answersThe presence of pollutants can affect the overall rate of biodegradation. Organic contaminants, such as aromatic hydrocarbons, pesticides, and synthetic dyes, are not easily biodegradable and can accumulate in ecosystems, causing toxic symptoms in organisms, including humans. Microbial degradation processes play a central role in the biodegradation of environmental pollutants, and the types of enzymes and pathways utilized by microbes are key factors in this process. Xenobiotics, which include pollutants like carcinogens, drugs, and pesticides, are known for their persistence and can remain in the environment for prolonged periods. The slow kinetics of degradation and high toxicity of xenobiotics make their removal from contaminated environments challenging. However, alternative technologies, such as bio-electrochemical systems, show promise in improving the kinetics of biodegradation for rapid removal of xenobiotic contaminants from the environment.What potential cellular events can be answered by rna protein discordance?
4 answersRNA-protein discordance can provide insights into potential cellular events such as regulatory functions and protein-protein interactions. The concentration of a protein in the cytoplasm is influenced by various co- and post-translational events, including folding efficiency, biochemical modification, complexation with other components, degradation, and transport. These events can cause the protein concentration to deviate from what would be expected based solely on mRNA translation. The dynamics of these deviations can create patterns that reflect regulatory functions. Additionally, the discordance between mRNA and protein levels can be attributed to delayed protein synthesis and degradation, which can be understood through systematic classification and kinetic modeling. Understanding the relationship between mRNA and protein levels can help predict protein levels in differentiated cell types and uncover protein-level regulation in cellular differentiation.What are the differences between microarray and RNA-seq?
3 answersRNA-seq and microarray are both techniques used for gene expression studies, but they have some key differences. RNA-seq is a newer technology that uses high-throughput sequencing to detect and quantify transcriptional activity in the cell. It offers advantages such as less noisy data, the ability to detect new transcripts and coding regions, and not requiring pre-determination of the transcriptomes of interest. On the other hand, microarray technology is older and has some limitations. It uses hybridization-based methods to measure gene expression and requires pre-determined target sequences. While microarrays have been widely used in the past, RNA-seq has become the platform of choice for many new experiments due to its reduced background noise and increased precision. RNA-seq outputs sequencing reads, while microarrays provide continuous fluorescent intensities. Overall, RNA-seq offers greater flexibility and sensitivity compared to microarrays, making it a preferred choice for gene expression analysis.