What is folate from culture of S cerevisiae mean?
Answers from top 6 papers
More filters
| Papers (6) | Insight |
|---|---|
| Therefore, folate catabolism is emerging as an important component in the regulation of intracellular folate concentrations and whole-body folate status. | |
57 Citations | Proper folate status is therefore necessary for a broad range of biological functions that go beyond the biochemistry of folate. |
75 Citations | This is the first report of a yogurt naturally bio-enriched in folate using native folate producing starter cultures. |
| These effects were accompanied by altered levels of several folate-metabolizing enzymes, indicating that the observed metabolic reprogramming may result from both decreased folate availability and altered folate metabolism. | |
119 Citations | Different starter cultures, however, might explain some of the variations in folate content and folate forms. |
137 Citations | It was concluded that the increase of folate content during fermentation was mainly due to folate synthesis by yeasts. |
Related Questions
Isolation and characterization of folic acid producing lactic acid bacteria5 answersLactic acid bacteria (LAB) have been extensively studied for their ability to produce folate, a vital nutrient. Various studies have isolated and characterized folate-producing LAB from different sources. Research has shown that LAB strains differ in their folate synthesis capabilities due to strain-dependent factors and the presence of specific folate biosynthetic genes. Additionally, LAB isolates have been identified from local food sources, showcasing extracellular folate production ranging from 10.37 to 74.2 µg/mL. Furthermore, LAB strains like Lactobacillus rhamnosus and Lactobacillus plantarum have been highlighted for their probiotic potential and significant folate production, making them suitable for food supplementation and infant weaning foods. These findings emphasize the importance of screening and characterizing folate-producing LAB for potential applications in functional foods and addressing folate deficiency concerns.
Can lactic acid bacterias augment folates in plants?5 answersLactic acid bacteria (LAB) have the potential to enhance folate levels in plants through biofortification. LAB strains such as Lactobacillus casei, Lactobacillus plantarum, and others have been shown to synthesize folates, including the natural form 5-methyltetrahydrofolate (5-MTHF). Additionally, various LAB strains have been identified for their ability to produce folates during fermentation, with differences observed based on species and strains. Studies have demonstrated that LAB, like Lactobacillus plantarum, can increase folate levels in fermented milk, showcasing the potential for folate enhancement in plant-based products. However, the folate production by LAB is influenced by factors such as the fermentation medium, presence of precursors, and fermentation time, which can impact the effectiveness of folate biosynthesis in plants.
Is there an interaction between alcohol, folate and cancer?5 answersThere is evidence of an interaction between alcohol, folate, and cancer. High folate intake is associated with a reduced risk of colorectal cancer, particularly in individuals with medium or high alcohol consumption. Alcohol consumption, on the other hand, increases the risk of colorectal cancer. Folate is hypothesized to accelerate cell proliferation in colorectal cancer by supporting DNA synthesis, while alcohol is also linked to gastrointestinal epithelial proliferation. The interaction between alcohol and folate appears to be important in colorectal cancer risk, with a potential negative interaction observed for distal/rectal tumors. These findings suggest that folate intake may have a protective effect against colon cancer, especially in individuals with middle or high alcohol consumption, but further confirmation is needed.
What is folic acid used for?4 answersFolic acid is used for various purposes in human health. It plays a crucial role in the prevention of neural tube defects, megaloblastic anemia, and certain cancers. In patients with chronic kidney disease (CKD) and anemia, folic acid is used as part of the treatment to support nucleoprotein synthesis and erythropoiesis maintenance. Folic acid has also been found to have an analgesic effect in bone cancer pain, making it a potential therapeutic strategy for pain relief in cancer patients. During pregnancy, folic acid supplementation is important for preventing fetal congenital defects, reducing the risk of spontaneous abortions, and supporting appropriate fetal growth and development. Additionally, folic acid supplementation has been investigated for its potential role in reducing the risk and severity of preeclampsia, although the optimal dose for prevention is still uncertain. In the context of COVID-19, folic acid has been studied for its potential benefits in terms of disease severity and associated conditions such as pulmonary hypertension and hyper-homocystinemia.
Alzheimer disease have any relation with folate status?4 answersAlzheimer's disease (AD) is associated with folate deficiency/possible deficiency, as indicated by lower plasma/serum folate levels in AD patients compared to controls. Folate deficiency/possible deficiency increases the risk for AD, while sufficient intake of folate is a protective factor against AD. Genetic susceptibilities in the folate pathway, specifically an abnormal SNP in methylene tetrahydrofolate dehydrogenase 1 (MTHFD1), are significantly predictive of AD. In AD, there is a decrease in critical folate binding proteins and enzymes in the cerebrospinal fluid (CSF), as well as a switch in the pathway of folate supply to the cerebral cortex. However, the association between vitamin B12 and folate levels and the development and progression of AD is inconsistent. Variations in markers of B12 and folate status are not associated with cognitive dysfunction and brain atrophy in AD patients.
What is folate?5 answersFolate is a B vitamin that plays a crucial role in various metabolic processes in the body, including DNA and RNA synthesis, amino acid interconversions, methylation reactions, and the generation and use of formate. It is essential for the normal functioning of the body and the maintenance of genomic integrity. Folate deficiency can lead to megaloblastic anemia, elevated plasma homocysteine levels, neurological and cognitive impairment, depression, and negative birth outcomes. Folic acid, the synthetic form of folate, is commonly used in fortification programs and dietary supplements to prevent folate deficiency. Adequate intake and absorption of folates are necessary for maintaining normal body functions and preserving genomic integrity. Natural food sources of folate include green leafy vegetables, citrus fruits, beans, nuts, and meat products. Folate insufficiency or deficiency is associated with an increased risk of neural tube defects, certain types of cancers, Alzheimer's disease, and cardiovascular disease.