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What is l plastin? 


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L-plastin is an actin-binding protein that plays a role in the dynamic rearrangement of the actin cytoskeleton. It is involved in tumor cell metastasis and is induced by Helicobacter pylori (H. pylori) infection in gastric cancer cells . L-plastin promotes gastric cancer cell proliferation and migration, as well as the growth and metastasis of gastric cancer . In T-cells, L-plastin regulates activation, migration, and immune synapse formation . L-plastin deficiency in zebrafish affects the macrophage response and may have consequences for organismal immunity . L-plastin is normally expressed in hematopoietic cells but is often ectopically expressed in malignant cancer cells of non-hematopoietic origin . Post-translational modification, such as phosphorylation, modulates L-plastin activity and is important for immune response, invasion, and metastasis formation . L-plastin may serve as a biomarker and therapeutic target in cancer .

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L-plastin is an actin-bundling protein that regulates T-cell activation and migration. It enhances actin polymerization and directly binds to the β2 chain of the integrin LFA-1 to support intercellular adhesion and immune synapse formation.
L-plastin is a leukocyte-specific calcium-dependent actin-bundling protein that affects immune cell migration.
L-plastin is an actin-binding protein (ABP) that is significantly induced in gastric cancer cells infected with Helicobacter pylori. It plays a role in promoting gastric cancer growth and metastasis.
L-plastin is an actin-binding protein (ABP) that is induced by Helicobacter pylori infection and plays a role in promoting gastric cancer growth and metastasis.

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