What is the appropriate measure of relative risk for a cohort study?
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The risk ratio can be a useful statistic for summarizing the results of cross-sectional, cohort, and randomized trial studies. | |
50 Citations | A competing-risk approach must be used to analyze the risk of events other than death in cohort studies, particularly when mortality rates are high. |
60 Citations | It is suggested that the summary statistics of a cohort mortality experience should include relative risk, attributable risk, and life expectancy. |
Given the same cohort method (historical prospective), cohort results vary widely according to different study designs, and this has implications for "generalizable" risk assessment or risk projections. | |
19 Citations | The case-cohort study design is a useful modification of the case-control design, which allows direct estimation of the risk ratio without the rare-disease assumption. |
15 Citations | Results of this paper may be useful in assessing the validity of the model of a common relative risk before combining several 2 x 2 tables or in designing a prospective study for detecting heterogeneity of relative risks. |
24 Citations | If there is reasonable agreement between cohort-specific relative risk estimates, a more powerful pooled summary estimate can be obtained. |
Related Questions
What is excess relative risk?3 answersExcess relative risk (ERR) is a measure used to quantify the association between exposure and disease. It involves both difference and ratio operations and is estimable in case-control studies. The ERR index remains constant across strata in a rare-disease case-control setting and can be regarded as a common effect parameter. It can be used to estimate attributable fraction indices with greater precision. The ERR index preserves the logical properties of ratio-type indices and is advocated for use as an effect measure in case-control studies of rare diseases. A Bayesian Poisson relative risk model can be used to display the excess relative risk associated with a unique exposure as a probability distribution in closed form. The relative excess risk is an alternative comparative measure that removes the background risk and applies to situations where an "unexposed" reference group is included.
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