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Open accessJournal ArticleDOI
12 Sep 2011-Reumatismo
15 Citations
Fish oil supplementation could represent a valuable support to the traditional pharmacological treatment of rheumatoid arthritis.
Krill oil did not modulate the levels of serum cytokines whereas consumption of fish oil increased the levels of IL-1α and IL-13.The study suggests that krill oil may be a useful intervention strategy against the clinical and histopathological signs of inflammatory arthritis.
We conclude that fish oil has small anti-inflammatory effects with at most a NSAID-saving potential.
Thus, we speculated that the antidenaturant activity of fish oil may be partly (in addition to the known effect on endogenous eicosanoid composition) responsible for its beneficial effects in rheumatoid arthritis and other rheumatic conditions.
Also, fish oils have protective clinical effects in occlusive cardiovascular disease, for which patients with RA are at increased risk. Implementation of the clinical use of anti-inflammatory fish oil doses has been poor.
Journal ArticleDOI
05 Aug 1988-JAMA
77 Citations
Preliminary observations also suggest a potential future role for fish oils in the treatment of some autoimmune diseases, such as atopic dermatitis, psoriasis, and rheumatoid arthritis.

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