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What is the history of malaria? 

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Malaria has a long history, with evidence of the disease dating back thousands of years . The name "malaria" originated from the belief that the disease was caused by bad air in swamps . Over time, various treatments and preventive measures have been developed. In China, the plant sweet sagewort was used to treat malaria as early as the second century BC . Quinine, derived from the bark of the cinchona tree, became an effective treatment in the 17th century . The discovery of the malaria parasite and the identification of the mosquito vector led to advancements in disease control . However, the evolution of drug-resistant parasites and insecticide-resistant mosquitoes has posed challenges to malaria eradication efforts . Despite progress, malaria remains a significant global health issue, particularly in Africa and some parts of Asia . Efforts to improve early diagnosis, treatment, and prevention are ongoing .

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Open accessJournal ArticleDOI
21 Jun 2019
162 Citations
The paper provides information on the history of malaria, stating that the sweet sagewort plant was used in China in the second century BC to treat malaria fever. Quinine later became an antimalarial drug.
Book ChapterDOI
01 Jan 2020
10 Citations
The history of malaria is discussed in the paper. It mentions that malaria is an ancient disease that was prevalent across the globe and caused significant morbidity and mortality. The first effective treatment, quinine, was introduced in Europe in the 17th century. The discovery of the malaria parasite and the identification of the mosquito vector led to improvements in disease control. However, the evolution of drug-resistant parasites and insecticide-resistant mosquitoes has led to the resurgence of malaria in some areas.
The paper provides an overview of the natural history of human malaria, including its long history of troubling humans for thousands of years.
The paper provides information about the history of malaria, including its existence since ancient times, its association with major military losses and the disappearance of nations, and the discovery of the disease's cause in 1880.
Open accessJournal ArticleDOI
01 Jun 2022
8 Citations
The paper provides a brief history of malaria, including its co-evolution with invertebrates and its impact on early hominids and modern humans. It also mentions progress in understanding the parasite, its transmission, and medicines, as well as the challenges of drug resistance and mosquito adaptation.

Related Questions

What is Malaria?4 answersMalaria is a tropical disease caused by a parasite transmitted by infected female Anopheles mosquitoes. The parasites multiply within red blood cells, leading to symptoms such as fever, headache, and vomiting. If left untreated, malaria can become life-threatening by disrupting the blood supply to vital organs. There are five species of Plasmodium that can cause malaria in humans, with Anopheles mosquitoes acting as the transmitting vectors. Diagnosis is typically done through microscopic detection of the parasite or rapid antigen diagnostic tests, and treatment depends on the infecting species and the severity of the disease. Malaria is present in more than 100 countries, with sub-Saharan Africa and Southeast Asia being the most affected regions. Each year, there are approximately 300 million cases and over 1 million deaths, with children and pregnant women being particularly vulnerable. Malaria is caused by a single-celled parasite from the genus Plasmodium, which has a complex life cycle involving both human and mosquito hosts.
Epidemiology of malaria?5 answersMalaria is an important infectious disease occurring in tropical and subtropical countries, with over 200 million cases and hundreds of thousands of deaths annually, mostly among children under 5 years old. The epidemiology of malaria has been a focus of recent research, particularly in relation to clinical malaria and its definition for evaluating control measures such as insecticide-treated materials and vaccines. Studies have shown different epidemiological patterns for severe malaria, with severe malarial anaemia occurring most frequently in areas of high transmission and in young children, while cerebral malaria predominates in areas of moderate transmission and in older children. Control strategies have faced challenges due to the unique epidemiological patterns in different regions, leading to the need for vector control and multidrug therapy. Malaria continues to be a health and economic issue, particularly in African countries, despite declining cases in recent years. The fight against malaria is a global goal, and efforts are being made to provide drugs and eliminate the disease.
What is the history of coffee?5 answersCoffee has a long and rich history that dates back to the 10th century. It originated in the mountains of Yemen and was initially consumed for its medicinal properties. Over time, coffee evolved from a medical treatment to a popular beverage. It gained cultural significance and became a symbol of conquest, independence, intellectual conversations, and conviviality. Coffee's cultural identity has shifted over time, and it has become a global marketplace icon. The European words for coffee were influenced by the Arabic and Turkish terms, and the modern European names for coffee emerged in the 17th century. Coffee drinking traditions have played a significant role in various regions, including the former Yugoslavia, where it has been a critical symbolic place-maker in diasporic and culturally dynamic contexts.
What are the causes of malaria?5 answersMalaria is caused by a parasite called Plasmodium, which is transmitted through the bites of infected mosquitoes. The parasites multiply in the liver and then infect red blood cells. Plasmodium parasites have a complex life cycle that requires both a human host and an insect host. The main global cause of mortality and morbidity, Plasmodium parasites have a complicated life cycle in both their hosts, the vertebrates, and their carriers, the mosquitoes. Infection with Plasmodium spp. parasites leads to the release of merozoites into the bloodstream following the rupture of infected red cells. Malaria is primarily caused by parasites of the genus Plasmodium, transmitted through the bites of female Anopheles mosquitoes.
What is malaria in pregnancy?3 answersMalaria in pregnancy refers to the occurrence of malaria infection in pregnant women. It is a significant public health concern with potential risks for both the mother and the fetus. Pregnant women with malaria may experience more severe symptoms and complications compared to non-pregnant individuals. These complications can include anemia, fever, preterm birth, fetal growth restriction, congenital infection, and even death of the mother and/or fetus. Malaria in pregnancy is caused by the Plasmodium parasites, particularly Plasmodium falciparum and Plasmodium vivax, which are the most common pathogens observed in pregnant patients. The diagnosis of malaria in pregnancy can be made through peripheral blood smears, and it should be considered in any febrile pregnant woman who has traveled to or resided in an endemic region. Preventive measures, such as chemoprophylaxis and counseling on risk reduction, are important in the management of malaria in pregnancy.
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