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What is the most efficient diagnostic test to determine metastasis in lung cancer? 

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In conclusion, our results showed the utility of the new bone markers in detecting bone metastasis and suggested that measurement of urinary NTx was valid diagnostic method of bone metastasis from lung cancer.
In conclusion, an OSNA assay using CK19 could be effective for molecular diagnosis of lymph node metastasis in lung cancer.
(18)FDG PET-CT has excellent diagnostic performance for diagnosis of distant metastases in patients with lung cancer.
EUS-FNA as a first test (after CT) has high diagnostic yield and accuracy for detecting lung cancer metastases to the mediastinum and distant sites.
This study provides an efficient and noninvasive strategy to detect tumor metastasis in LNs with greatly enhanced diagnostic accuracy.
In conclusion, we have developed an efficient and unbiased method to determine the metastasis burden in mouse lungs.
We describe an algorithm for the diagnosis and tumor-node-metastasis staging of lung cancer that uses procedures with the least invasiveness and cost with the highest diagnostic yields.
Open accessJournal ArticleDOI
Denise R. Aberle, Kathleen Brown 
32 Citations
There is an impetus to find a screening test that can detect non-small cell lung cancer in its early preclinical stages, when surgical resection is most likely to reduce lung cancer mortality.
Further studies with larger cohorts, including also more participants with early‐stage tumors, should be performed to increase the robustness of this noninvasive diagnostic tool and to determine its added value in the diagnostic chain for lung cancer.
Open accessPosted ContentDOI
Jing Wei, Na Ni, Linpei Zhang, Youhe Gao 
22 Apr 2018-bioRxiv
9 Citations
Our results provide the potential to detect early breast cancer lung metastasis, monitor its progression and differentiate it from the same cancer cells grown at other locations.

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