What is the population most at risk for E coli?
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| We found that children < 2 years of age were at highest risk of infection with E. coli O157:H7. | |
| The people most at risk for infection with this strain of E coli are the very young and very old, but anyone can become ill if infected. | |
| The presence of E. coli represents a significant public health risk. | |
61 Citations | E. coli O157:H7 may be more likely to cause disease outbreaks in this population because of the low inoculum required for clinical infection. |
| The circulation of pathogenic E. coli and antimicrobial resistance within bacterial population represents high risk to ecosystem and human health and highlights epidemiological surveillance and sanitary improvement. | |
96 Citations | The recipient of the potential pathogenic E. coli through food, the humans, are also of different risk of contracting diseases. |
| E. coli ST131, which has also been demonstrated in this study, poses a potential risk to this vulnerable population. | |
63 Citations | Foodborne proportions for most pathogens in this study were the same or lower than those estimated circa 2000 in Australia, with the greatest decline for non-STEC pathogenic E. coli. |
| The broilers E. coli population poses a potential zoonotic risk which could be transmitted to the community through the food chain. |
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How prevalent is ATCC strain of e.coli in the population and in the diseases community?5 answersThe prevalence of ATCC strain of E. coli varies depending on the specific strain being considered. Adherent-invasive E. coli (AIEC) strains, a subset of E. coli, have been implicated in inflammatory bowel disease (IBD) pathogenesis, with certain clones commonly found in healthy individuals and patients with community-acquired urinary tract infections (). On the other hand, AmpC β-lactamase-producing E. coli strains have a low prevalence, with plasmid acquisition being the main mechanism of AmpC production, and fluoroquinolone use identified as a risk factor for infection (). Enteropathogenic E. coli (EPEC) strains, including typical (tEPEC) and atypical (aEPEC) variants, have been found in children with diarrhea, with a shift towards atypical strains in recent years (). Additionally, the AIEC phenotype has been identified in patients with Crohn's disease (CD) and ulcerative colitis (UC), suggesting a potential role in these conditions (). The Escherichia coli sequence type 131 (ST131) clone, a pandemic strain, is prevalent worldwide, particularly among fluoroquinolone-resistant E. coli, causing various infections including urinary tract infections ().
How does the presence of Escherichia coli in domestic wastewater affect public health and the environment?4 answersThe presence of Escherichia coli in domestic wastewater poses a threat to public health and the environment. The incidence of drug-resistant bacteria, including antibiotic-resistant E. coli, is increasing in wastewater, which can contribute to the spread of antibiotic resistance in the environment. Wastewater treatment plants may not effectively eliminate antibiotic-resistant bacteria, leading to their persistence in water bodies. These antibiotic-resistant E. coli isolates can serve as reservoirs of resistance genes and pose potential threats to human and animal health. Additionally, the adaptation of E. coli strains to wastewater environments may enable them to survive treatment processes, such as chlorination and UV light exposure, further promoting their dissemination. The presence of E. coli in environmental waters indicates fecal pollution, but identifying the specific source of contamination, such as domestic wastewater, is crucial for effective contamination reduction. Overall, the presence of E. coli in domestic wastewater highlights the need for monitoring and early identification of antibiotic-resistant bacteria to mitigate the spread of resistance and protect public health and the environment.
What are the risks associated with eating street food contaminated with Escherichia coli?4 answersConsuming street food contaminated with Escherichia coli poses several risks to health. The presence of antibiotic-resistant E. coli strains in street food emphasizes the potential health hazards associated with their consumption. These strains can be potentially pathogenic, carrying virulence properties such as the hlyA gene and causing enteropathogenic infections. Additionally, the incidence of recent fecal contamination in street food is a concern, as it indicates poor hygiene practices and increases the risk of foodborne diseases. Street food vendors often operate with less structured food safety guidelines, leading to a higher prevalence of extended-spectrum-β-lactamase (ESBL) producing bacteria in these foods. ESBL-producing E. coli strains are resistant to multiple antibiotics, making them difficult to treat and increasing the chances of transferring antibiotic resistance to humans. Therefore, consuming street food contaminated with E. coli can result in foodborne illnesses and contribute to the spread of antibiotic resistance.
What are the prevalence of E.coli among hospitalized patients ??2 answersThe prevalence of E. coli among hospitalized patients varied across different studies. In a study conducted in two government hospitals in Delta State, Nigeria, E. coli accounted for 74.2% of the clinical isolates obtained from urine, blood, and wound samples. Another study conducted in Zagazig University Hospitals found that E. coli was the most common causative organism of urinary tract infections (UTIs) among both in-patients and out-patients. In a study conducted in Rasht, Iran, E. coli strains were isolated from patients hospitalized with various infections, and 51.9% of the strains showed extended-spectrum beta-lactamase (ESBL) activity. However, the prevalence of E. coli among hospitalized patients was not specifically mentioned in the study conducted on the Premier inpatient database. Lastly, a study conducted in Zabol, Iran, found that 99% of the UPEC isolates obtained from patients with urinary tract infections carried virulence genes associated with E. coli.
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