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What kills RNA virus? 

RNA silencing
RNA-dependent RNA polymerase
RNA
Virus
RNA virus

Answers from top 10 papers

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Papers (10)Insight
Open access•Journal Article•DOI
Isolation of virus-neutralizing RNAs from a large pool of random sequences.
Weihua Pan, Rebecca C. Craven, Qiu Qiu, Qiu Qiu, Carol B. Wilson, John W. Wills, Serguei Golovine, Jin Feng Wang 
05 Dec 1995-Proceedings of the National Academy of Sciences of the United States of America
147 Citations
The selected RNA and RNA analogs were shown to neutralize RSV by interacting with the virus, rather than by adversely affecting the host cells.
Open access•Journal Article•DOI
Influenza virus NS1 protein binds cellular DNA to block transcription of antiviral genes
Maria Anastasina, Nicolas Le May, Andrii Bugai, Yu Fu, Sandra Söderholm, Lana Gaelings, Tiina Öhman, Janne Tynell, Suvi Kyttanen, Matjaz Barboric, Tuula A. Nyman, Sampsa Matikainen, Ilkka Julkunen, Ilkka Julkunen, Sarah J. Butcher, Jean-Marc Egly, Denis E. Kainov 
01 Nov 2016-Biochimica et Biophysica Acta
30 Citations
Thus, we identified a previously undescribed strategy, by which RNA virus inhibits cellular transcription to escape antiviral response and secure its replication.
Book Chapter•DOI
Tobacco rattle virus (TRV)-based virus-induced gene silencing.
Shawn Bachan, Savithramma P. Dinesh-Kumar 
01 Jan 2012-Methods of Molecular Biology
61 Citations
This process implies that a virus can trigger the host plant's RNA-silencing machinery and ultimately become the target of RNA silencing.
Open access•Journal Article•DOI
Protection against lethal influenza virus challenge by RNA interference in vivo.
Stephen Mark Tompkins, Chia-Yun Lo, Terrence M. Tumpey, Suzanne L. Epstein 
08 Jun 2004-Proceedings of the National Academy of Sciences of the United States of America
392 Citations
RNA interference is an effective means of suppressing virus replication in vitro.
Open access•Journal Article•DOI
Inhibition of mouse hepatitis virus multiplication by an oligonucleotide complementary to the leader RNA.
Tetsuya Mizutani, Masanobu Hayashi, Akihiko Maeda, Tadashi Yamashita, Hiroshi Isogai, Shigeo Namioka 
15 Jun 1992-Journal of Veterinary Medical Science
12 Citations
These results showed that antisense oligonucleotide against the leader RNA reduced the multiplication of positive-stranded RNA virus, MHV.
Open access•Journal Article•DOI
Conservation of a Triple-Helix-Forming RNA Stability Element in Noncoding and Genomic RNAs of Diverse Viruses
Kazimierz T. Tycowski, Mei-Di Shu, Sumit Borah, Mary Shi, Joan A. Steitz 
26 Jul 2012-Cell Reports
87 Citations
One is in an insect picorna-like positive-strand RNA virus, suggesting that the ENE can counteract cytoplasmic as well as nuclear RNA decay pathways.
Open access•Journal Article•DOI
Nuclease escape elements protect messenger RNA against cleavage by multiple viral endonucleases.
Mandy Muller, Britt A. Glaunsinger 
25 Aug 2017-PLOS Pathogens
21 Citations
These findings highlight how RNA elements can selectively control transcript abundance in the background of widespread virus-induced mRNA degradation.
Open access•Journal Article•DOI
Antiviral role of plant-encoded RNA-dependent RNA polymerases revisited with deep sequencing of small interfering RNAs of virus origin.
Feng Qu
10 Sep 2010-Molecular Plant-microbe Interactions
66 Citations
In conclusion, these studies established that RDR1 and RDR6 function synergistically to contain RNA virus infections through the RNA silencing-based antiviral defense.
Open access•Journal Article•DOI
CpG Dinucleotides Inhibit HIV-1 Replication through Zinc Finger Antiviral Protein (ZAP)-Dependent and -Independent Mechanisms
Mattia Ficarelli, Irati Antzin-Anduetza, Rupert Hugh-White, Andrew E. Firth, Helin Sertkaya, Harry Wilson, Stuart J. D. Neil, Reiner Schulz, Chad M. Swanson 
28 Feb 2020-Journal of Virology
55 Citations
IMPORTANCE Some RNA virus genomes are suppressed in the nucleotide combination of a cytosine followed by a guanosine (CpG), indicating that they are detrimental to the virus.
Journal Article•DOI
The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen.
Shane Crotty, David Maag, Jamie J. Arnold, Weidong Zhong, Johnson Y. N. Lau, Zhi Hong, Raul Andino, Craig E. Cameron 
01 Dec 2000-Nature Medicine
791 Citations
Thus, mutagenic ribonucleosides may represent an important class of anti-RNA virus agents.

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