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What population is most susceptible to the measles virus? 

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A small but important proportion of healthcare workers are susceptible to measles.
This outbreak in a community with low-vaccination rates affected largely the pediatric-age population, compatible with acquisition of measles immunity by adult members due to prior wild-type measles infection.
Interpretation Populations without endemic measles transmission can accumulate substantial susceptibility and be at risk for large outbreaks when measles virus is imported.
Despite the low percentage of susceptibility among those born before 1957, the 144 susceptible individuals in this group also are at risk for measles transmission.
Our data indicate that Poland is approaching measles elimination, but measles virus circulation is still sustained in a vulnerable population.
We demonstrate the transmission of measles virus in a population in which the two-dose MMR vaccination coverage rate was 80% and how even vaccinated individuals may be at risk of contracting measles once transmission has been established.
The identification of groups susceptible to the measles virus in young adults could lead to outbreaks as a result of importing the virus.
Open accessBook ChapterDOI
Stephen J. Russell, Kah Whye Peng 
163 Citations
From a safety perspective, population immunity provides an excellent defense against measles spread from patient to carers and, in 50 years of human experience, reversion of attenuated measles to a wild-type pathogenic phenotype has not been observed.
Our findings underline the epidemiological significance of suboptimal vaccination coverage in anthroposophic communities and in older age groups of the general population in facilitating measles virus circulation.
Our analyses suggest that measles Rv often includes or exceeds one (0.18-3.92) despite high levels of population immunity.

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