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What receptors does Lunesta work? 

Signal transduction
GABAA receptor
Receptor
gamma-Aminobutyric acid
Agonist

Answers from top 10 papers

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Papers (10)Insight
Journal Article•DOI
Glutamate-receptor genes in plants.
Hon-Ming Lam, Joanna C. Chiu, Ming-Hsiun Hsieh, Lee A. Meisel, Igor C. Oliveira, Michael Shin, Gloria M. Coruzzi 
12 Nov 1998-Nature
323 Citations
Our findings also help to explain why neuroactive compounds made by plants work on receptors in human brains.
Journal Article•DOI
An endogenous substance from porcine brain antagonizes the anticonvulsant effect of diazepam
Julia Nagy, Julianna Kardos, Gábor Maksay, Miklós Simonyi 
01 May 1981-Neuropharmacology
11 Citations
ES does not seem to be an endogenous ligand of benzodiazepine receptors; it probably exerts its effect via GABA receptors.
Open access•Journal Article•DOI
The 5-HT(7) receptor in learning and memory.
Amanda J. Roberts, Peter B. Hedlund 
01 Apr 2012-Hippocampus
89 Citations
While more work is required, it appears that 5‐HT7 receptors are particularly important in allocentric representation processes.
Open access•Journal Article•DOI
A retinoid-related molecule that does not bind to classical retinoid receptors potently induces apoptosis in human prostate cancer cells through rapid caspase activation.
Richard G. Keedwell, Yi Zhao, Lisette A. Hammond, Suofu Qin, Kwok-Yin Tsang, Armin Reitmair, Yanira Molina, Yumiko Okawa, Larissa I. Atangan, Dixie-Lee Shurland, Kaisheng Wen, D. Michael A. Wallace, Roger Bird, Roshantha A.S. Chandraratna, Geoffrey Brown 
01 May 2004-Cancer Research
32 Citations
The mechanism(s) of action of these compounds does not appear to involve retinoic acid receptors (RARs) and retinoid X receptors (RXRs), although some investigators disagree with this view.
Open access•Journal Article•DOI
Activation of the GLP-1 receptor by a non-peptidic agonist
Peishen Zhao, Yi Lynn Liang, Matthew J. Belousoff, Giuseppe Deganutti, Madeleine M. Fletcher, Francis S. Willard, Michael Gregory Bell, Michael E. Christe, Kyle W. Sloop, Asuka Inoue, Tin T. Truong, Lachlan Clydesdale, Sebastian G.B. Furness, Arthur Christopoulos, Ming-Wei Wang, Ming-Wei Wang, Laurence J. Miller, Christopher A. Reynolds, Radostin Danev, Patrick M. Sexton, Patrick M. Sexton, Denise Wootten, Denise Wootten 
08 Jan 2020-Nature
98 Citations
This work alters our understanding of the events that drive the activation of class B receptors.
Journal Article•DOI
Inhibition of noradrenaline release via presynaptic 5-HT1B receptors of the rat vena cava.
Gerhard J. Molderings, Klaus Fink, Eberhard Schlicker, Manfred Göthert 
01 Sep 1987-Naunyn-schmiedebergs Archives of Pharmacology
77 Citations
Cyanopindolol may act as a partial agonist at these receptors, as it does at the facilitatory prosynaptic β-adrenoceptors.
Journal Article•DOI
Influence of GABAAReceptor γ2Splice Variants on Receptor Kinetics and Isoflurane Modulation
Claudia Benkwitz, Matthew I. Banks, Robert A. Pearce 
01 Oct 2004-Anesthesiology
33 Citations
The results indicate that subunit composition does substantially influence modulation of GABAA receptors by isoflurane.
Open access•Journal Article•DOI
GABA acts as a ligand chaperone in the early secretory pathway to promote cell surface expression of GABAA receptors
Randa S. Eshaq, Letha D. Stahl, Randolph Stone, Sheryl S. Smith, Lucy C. Robinson, Nancy J. Leidenheimer 
30 Jul 2010-Brain Research
43 Citations
Consistent with an intracellular action of GABA, we show that GABA does not act by stabilizing surface receptors.
Journal Article•DOI
Selective allosteric enhancement of the binding and actions of acetylcholine at muscarinic receptor subtypes
Nigel J. M. Birdsall, Tim Farries, Tim Farries, Parviz Gharagozloo, Shinsaku Kobayashi, Donald Kuonen, Sebastian Lazareno, Angela Popham, Masahiko Sugimoto 
21 Feb 1997-Life Sciences
61 Citations
In addition it binds to, but does not affect, the properties of m4 receptors, thereby demonstrating neutral cooperativity and an 'absolute' selectivity of action at m3 receptors over m4 receptors.
Journal Article•DOI
Cucurbit[7]uril⋅guest pair with an attomolar dissociation constant
Liping Cao, Marina Šekutor, Peter Y. Zavalij, Kata Mlinarić-Majerski, Robert Glaser, Lyle Isaacs 
20 Jan 2014-Angewandte Chemie
316 Citations
This work further blurs the lines of distinction between natural and synthetic receptors.

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