What will happen if your motor neurons are exposed to Dendrotoxin?
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52 Citations | Vigorous physical activity could potentiate the effect of a toxin to motor neurons by any of several mechanisms, especially if the toxin's effects were mediated through excitation. |
24 Citations | In conclusion, the present data on dendrotoxin K, together with the previously described pattern of neurotoxicity for alpha-dendrotoxin, show that these homologues act via different mechanisms and, thus, can be used effectively as complementary tools to study seizures and neuronal cell death. |
33 Citations | Dendrotoxin is a very powerful toxin that acts effectively at the level of the limbic system. |
19 Citations | Therefore, neurons may be exposed to this agent. |
This acceptor is implicated in the action of toxin because its affinities for dendrotoxin congeners are proportional to their central neurotoxicities and potencies in reducing the transient, voltage-dependent K conductance. | |
49 Citations | Notably, this heterogeneity can be related to electrophysiological evidence for the presence in neurons of multiple, dendrotoxin-sensitive, K+ conductances, though some of these remain to be shown directly in brain preparations. |
108 Citations | In native cells, dendrotoxin appears preferentially to block inactivating forms of K+ current. |
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