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Which diseases can be cured using quinine?

Pharmacokinetics

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Plasmodium falciparum

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Journal Article•DOI Quinine Sensitivity: A New Cause of the Hemolytic Uremic Syndrome Richard H. Aster 01 Aug 1993-Annals of Internal Medicine 27 Citations	It can therefore be argued that quinine should remain available for this therapeutic indication.
Journal Article•DOI Pharmacokinetics of quinine in African patients with acute falciparum malaria. Chinedum P. Babalola, Oluseye O. Bolaji, F.A. Ogunbona, Akintunde Sowunmi, O. Walker - Show less +4 more 01 Jun 1998-Pharmacy World & Science 31 Citations	It also confirms that malaria significantly alters the pharmacokinetics of quinine in humans.
Journal Article•DOI Quinine--acute self-poisoning and ocular toxicity. M A Mackie, J. F. Davidson, J Clarke - Show less +2 more 01 Feb 1997-Scottish Medical Journal 17 Citations	These observations, combined with the doubtful clinical efficacy of quinine, suggest that its continued widespread use should be reappraised.
Journal Article•DOI Susceptibility of Plasmodium falciparum to quinine in vitro: effects of drug concentrations and time of exposure. Erasto Mapaba, Urban Hellgren, Anita Landberg-Lindgren, Lars Rombo - Show less +3 more 01 Jan 1995-Transactions of The Royal Society of Tropical Medicine and Hygiene 17 Citations	These experiments suggest that it might be preferable to reduce each dose rather than the duration of treatment in areas where P. falciparum is susceptible to quinine.
Journal Article•DOI Quinine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan Ishag Adam, Isam M. A. Salih, Mustafa I. Elbashir - Show less +2 more 01 Oct 2005-Transactions of The Royal Society of Tropical Medicine and Hygiene 23 Citations	The present results and those of earlier investigations indicate that the response to quinine in this area may be faltering.
Journal Article•DOI Pharmacokinetics and Clinical Toxicity of Quinine Overdosage: Lack of Efficacy of Techniques Intended to Enhance Elimination D. N. Bateman, Peter G. Blain, K. W. Woodhouse, M. D. Rawlins, H. Dyson, R. Heyworth, L. F. Prescott, A. T. Proudfoot - Show less +7 more 01 Feb 1985-QJM: An International Journal of Medicine 69 Citations	It is concluded that techniques advocated to increase quinine elimination are ineffective in the management of quinine poisoning.

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