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Results suggest that optimizing the dosing of pyrazinamide, the injectables, and isoniazid for drug-resistant tuberculosis is a high priority.
Two-drug up to seven-drug therapy may be indicated for a case of tuberculosis, depending on evidence of the presence of multiple drug resistance.
which have antimicrobial activity; thus may be useful in control of tuberculosis.
This result is comparable to drugs commonly used in tuberculosis treatment.

Related Questions

How effective is TB47 in treating mycobacterium infections compared to other available drugs?5 answersTB47, a pyrazolo[1,5-a]pyridine-3-carboxamide, shows promising efficacy against mycobacterial infections. In the context of Mycobacterium tuberculosis, TB47 demonstrates potent bactericidal activity, especially when combined with clofazimine and linezolid, leading to fast sterilization without relapse. Additionally, TB47 exhibits activity against Mycobacterium abscessus, enhancing the effectiveness of clofazimine both in vitro and in vivo. However, TB47 is reported to be ineffective against M. abscessus and does not enhance clofazimine activity. Furthermore, TB47 displays high bactericidal efficacy against Mycobacterium ulcerans, significantly reducing bacterial burden in vivo. Overall, TB47 shows promise as a potential treatment option for mycobacterial infections, particularly when used in combination with other drugs like clofazimine and linezolid.
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