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Which foods are rich in the antioxidant vitamin C?

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Journal Article•DOI Vitamin C exhibits pro-oxidant properties Ian D. Podmore, Helen R. Griffiths, Karl E. Herbert, Nalini Mistry, Pratibha Mistry, Joseph Lunec - Show less +5 more 09 Apr 1998-Nature 782 Citations	However, we report here that vitamin C administered as a dietary supplement to healthy humans exhibits a pro-oxidant, as well as an antioxidant, effect in vivo.
Open access•Journal Article•DOI Reply: Does vitamin C have a pro-oxidant effect? Ian D. Podmore, Helen R. Griffiths, Karl E. Herbert, Nalini Mistry, Pratibha Mistry, Joseph Lunec - Show less +5 more 17 Sep 1998-Nature 17 Citations	On this basis, vitamin C seems to act as both a pro-oxidant and an antioxidant in vivo.
Journal Article•DOI The antioxidant role of vitamin C Adrianne Bendich, L.J. Machlin, O. Scandurra, G.W. Burton, D.D.M. Wayner - Show less +4 more 01 Jan 1986-Advances in Free Radical Biology & Medicine 639 Citations	This review presents evidence which supports the importance of vitamin C as a component of the overall antioxidant protective mechanisms found in cells and tissues.
Journal Article•DOI Roles of Antioxidants on Prolonged Storage of Avian Spermatozoa In Vivo and In Vitro Christelle Breque, Peter F. Surai, J. P. Brillard - Show less +2 more 01 Nov 2003-Molecular Reproduction and Development 123 Citations	Preliminary observations have revealed the presence of a specific antioxidant system at these sites in which vitamin C could exert a major role.
Journal Article•DOI The antioxidant role of vitamin C Adrianne Bendich, L.J. Machlin, O. Scandurra, G.W. Burton, D.D.M. Wayner - Show less +4 more 01 Jan 1986-Advances in Free Radical Biology & Medicine 639 Citations	The data are consistent and form a strong consensus for investigating the importance of the antioxidant function of vitamin C in the maintenance of human health.
Journal Article•DOI Plasma-Saturating intakes of vitamin C confer maximal antioxidant protection to plasma. Carol S. Johnston, Sarah K. Cox - Show less +1 more 01 Dec 2001-Journal of The American College of Nutrition 32 Citations	These data indicate that the antioxidant protection afforded by short-term vitamin C supplementation is maximal at the 500–1000 mg dosage range.
Open access•Journal Article•DOI Antioxidant and pro-oxidant activity of Vitamin C in oral environment. Aratirika Chakraborthy, Pratibha Ramani, Herald J Sherlin, Priya Premkumar, Anuja Natesan - Show less +4 more 01 Jul 2014-Indian Journal of Dental Research 69 Citations	The data validates the role of Vitamin C as an antioxidant under physiologic conditions exhibiting a cross over role as a pro-oxidant in pathological conditions.

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What is benefits of vitamin C?5 answersVitamin C offers a multitude of benefits to the human body. It acts as an essential enzyme cofactor for various biochemical reactions, including collagen biosynthesis, carnitine and catecholamine synthesis, and cholesterol metabolism. Furthermore, vitamin C plays a crucial role in antioxidant defense by scavenging reactive oxygen and nitrogen species, modulating iron absorption, and participating in DNA and histone remodeling. Studies have shown that vitamin C intake is associated with reduced risks of all-cause mortality, cardiovascular diseases, and various cancers, while also benefiting respiratory, neurological, musculoskeletal, and renal health outcomes. Additionally, vitamin C has demonstrated promising effects in immune support, skin aging reduction, osteoporosis risk reduction, and as an adjunct treatment in conditions like sepsis and cancer.

Are there health benefits to vitamin c supplements?5 answersVitamin C supplementation has been associated with various health benefits. It has been shown to improve cardiovascular health by reducing inflammation and blood pressure. Additionally, vitamin C intake has been linked to a reduced risk of all-cause mortality, cardiovascular disease, and certain types of cancer. Vitamin C supplementation has also been found to have a positive effect on the duration of respiratory tract infections, leading to shorter illness duration. Furthermore, high-dose vitamin C supplementation has been shown to modulate the composition of the gut microbiota, favorably affecting bacterial populations associated with anti-inflammatory properties and gut health. However, the evidence for vitamin C supplementation in other areas such as cognitive performance, quality of life, and eye diseases is limited. Overall, while vitamin C supplementation has demonstrated several health benefits, further research is needed to fully understand its potential effects in different populations and health conditions.

What are the benefits of taking vitamin C?4 answersVitamin C has been found to have various benefits for health. It acts as an antioxidant, supporting the immune system and reducing inflammation. Studies have shown that vitamin C intake is associated with a reduced risk of all-cause mortality, cardiovascular disease, and certain types of cancer. It has also been shown to slow down skin aging and reduce the risk of osteoporosis. In patients with sepsis, vitamin C administration has been found to have clinical benefits, such as a reduction in SOFA score and mortality. However, the use of high-dose intravenous vitamin C in critically ill patients with COVID-19 did not show a mortality benefit or improvement in oxygenation. Further research is needed to confirm the effects of vitamin C and its optimal use in different health conditions.

What are the different types of antioxidants in food?3 answersAntioxidants in food can be classified into different types. Phenolic compounds (PCs) are one type of antioxidant that acts by reacting with free radicals through various mechanisms. Synthetic antioxidants such as tert-butyl hydroquinone (TBHQ), butylated hydroxy toluene (BHT), propyl gallate (PG), and butylated hydroxy anisole (BHA) are commonly used in food preservation. Microbes, including bacteria, actinomycetes, blue green algae, fungi, and yeasts, have the ability to produce natural antioxidants. Plant foods are rich in compounds with antioxidant potential, such as phenolic chemicals, phytates, and biopeptides. Additionally, vitamins C and E, α-carotene, lycopene, and polyphenols are important sources of antioxidants in food.

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Docking Study with IC50 VALUE

The docking study conducted in various research papers aimed to analyze the binding interactions of different compounds with specific target proteins, correlating these interactions with their IC50 values. For instance, in the study by Xia et al., compound 4 exhibited strong antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 2 μg/mL, and its docking to the KatG enzyme was highlighted as a key factor in its efficacy. Similarly, Taha et al. synthesized bisindole analogs and evaluated their anti-leishmanial potential, showing outstanding inhibitory activity with IC50 values ranging from 0.7 ± 0.01 to 13.30 ± 0.50 µM, with molecular docking aiding in understanding the binding interactions of these active molecules. These studies demonstrate the importance of molecular docking in elucidating the mechanisms underlying the IC50 values of bioactive compounds.Regarding Antiglycation Assay, what are the IC50 (ug/mL) values of different Rubiaceae species?

The IC50 (ug/mL) values of different Rubiaceae species in terms of antiglycation assay are as follows: Psychotria zombamontana had the best antioxidant activity with an IC50 value of 1.77 μg/mL. The methanol extracts and infusions of Hyperacanthus species showed very strong antioxidant activity with IC50 values ranging from 9.36 to 11.18 μg/mL. Additionally, the shoot extracts of Plectocomia himalayana exhibited good free radical scavenging activity with IC50 values of 117.73 μg/mL for cold methanol extract and 163.16 μg/mL for hot methanol extract. These values indicate the potency of these Rubiaceae species in terms of antiglycation activity, highlighting their potential as sources of natural antioxidants.How to decrease post harvest losses in guava?

To decrease post-harvest losses in guava, various strategies can be employed based on the research findings. Coating guavas with 2% chitosan and 0.02% nano-SiO2 film has been shown to be effective in maintaining quality parameters like skin color, firmness, ascorbic acid content, and taste scores, while reducing weight loss and decay incidence. Additionally, post-harvest chemical treatments such as calcium chloride at 3.0% dip for 5 minutes have demonstrated positive effects on physical parameters, total soluble solids, acidity, ascorbic acid content, and sensory traits of guavas, ultimately increasing shelf life. Furthermore, treating guavas with boric acid at 300 ppm has been found to decrease physiological weight loss during storage, contributing to minimizing post-harvest losses. Considering drop height and impact surface during handling can also help reduce guava quality deterioration.What is carotenoids, source, and application?

Carotenoids are a class of isoprenoid pigments that range in color from yellow to red and are widely distributed among living organisms, playing crucial roles in biological systems. They are recognized for their antioxidant properties, which contribute to their applications across various sectors including food, pharmaceuticals, and cosmetics. Carotenoids are naturally synthesized by plants and microorganisms, serving not only as colorants but also as agents with potential health benefits, such as reducing the risk of certain diseases like cancer, cataracts, and macular degeneration. Humans cannot synthesize carotenoids de novo, thus they must be obtained through diet, primarily from fruits and vegetables, which are significant sources of these compounds. The extraction and production of carotenoids have evolved to include sustainable and green technologies, moving away from conventional methods that often use hazardous solvents. Recent advancements have highlighted the use of greener solvents and bioprocessing technologies to improve the yield and efficiency of carotenoid production, making the process safer for consumers and the environment. Microbial synthesis of carotenoids presents an alternative to plant-based sources, offering advantages such as controlled cultivation conditions, reduced production times, and the ability to utilize lignocellulosic waste as a substrate, thereby enhancing sustainability. Carotenoids find extensive applications in the food, pharmaceutical, and cosmetic industries due to their colorant properties, antioxidant activity, and health-promoting effects. They are used in products ranging from food additives to skin care formulations, where they help in preventing premature skin aging induced by oxidative stress. The exploration of novel sources, including marine organisms and extremophiles from environments like the Caatinga domain, has opened new avenues for the sustainable production of carotenoids, aligning with global efforts towards environmental conservation and the development of green technologies.How do preservative vegetables chips compare nutritionally to traditional junk foods?

Preserved vegetable chips offer a more nutritious alternative to traditional junk foods. Preservation methods like salting, sun drying, ultrasonication with nanoparticles, and microwave treatment can help retain nutrients and extend shelf life. While traditional cooking and storage methods may lead to significant nutrient losses in vegetables, the incorporation of fruit and vegetable by-products in extruded foods can enhance their fiber and antioxidant content, potentially improving their health benefits. Additionally, innovative preservatives made from natural ingredients like citrus peels, banana peels, and aloe vera can effectively prolong the shelf life of fruits and vegetables while minimizing nutrient loss. Therefore, preserved vegetable chips can provide a balanced mix of nutrients, offering a healthier snacking option compared to traditional junk foods.What type of synthetic material in the future might rely on more farming?

In the future, the development of biobased soft materials derived from crops is anticipated to rely more on farming for their production. These materials, such as glycolipids generated from industrial byproducts like cashew nut shell liquid, offer unique properties like self-assembly into various nanoarchitectures, gels, and liquid crystals. By utilizing a "chiral pool" of carbohydrates and enzyme catalysis, amphiphilic products can be synthesized from biobased feedstock, showcasing the potential for innovative materials sourced from renewable agricultural resources. The interdisciplinary collaboration between scientists in organic synthesis, soft materials research, and green chemistry is crucial for advancing the development of functional materials from underutilized crop-based renewable feedstock, aligning with the shift towards sustainable and environmentally friendly manufacturing practices.Has the role of vitamin C been studied for postoperative surgical wound healing in adults?

Vitamin C has been extensively studied for its role in postoperative surgical wound healing in adults. Research indicates that vitamin C supplementation can improve healing outcomes in various pathologies, particularly pressure ulcers. Studies have shown that vitamin C plays a crucial role in collagen formation, antioxidant properties, and modulation of pain, contributing to enhanced wound healing in postoperative care. Additionally, experiments on rats have demonstrated that both oral and subcutaneous administration of vitamin C can accelerate the healing time of surgical wounds, emphasizing its effectiveness in wound healing processes. Overall, the evidence suggests that vitamin C supplementation may be beneficial for promoting better postoperative surgical wound healing outcomes in adults, highlighting its potential significance in clinical practice.What is the molecular mechanism behind the correlation between diabetes mellitus and oxidative stress?

The molecular mechanism behind the correlation between diabetes mellitus (DM) and oxidative stress (OS) is multifaceted, involving an intricate interplay of biochemical processes that exacerbate the pathophysiology of DM through the overproduction of reactive oxygen species (ROS) and the impairment of the antioxidant defense system. In the context of type 2 diabetes mellitus (T2DM), chronic hyperglycemia and an inadequate response to insulin lead to insulin resistance, a condition significantly contributed to by oxidative stress due to an imbalance between free radical production and the antioxidant system. This imbalance results in the alteration of cellular components, including lipids, proteins, and DNA, ultimately causing cellular dysfunction and the progression of DM. Oxidative stress in DM is characterized by the excessive generation of ROS, such as hydrogen peroxide and the superoxide anion, which introduce chemical changes in virtually all cellular components, causing deleterious effects on the islets of β-cells and affecting insulin production. This is further exacerbated by the activation of various signaling pathways under hyperglycemic conditions, such as nuclear factor-κβ (NF-κβ) and protein kinase C (PKC), which are also activated by ROS, leading to insulin resistance. Additionally, the overproduction of mitochondrial superoxide in metabolic tissues contributes to the development of both microvascular and cardiovascular complications associated with diabetes. The pathogenesis of diabetic complications, such as retinopathy, is also critically influenced by oxidative stress, which results from metabolic abnormalities induced by hyperglycemia. These include increased flux through the polyol and hexosamine pathways, hyper-activation of PKC isoforms, and accumulation of advanced glycation end products (AGEs), alongside the repression of the antioxidant defense system. Furthermore, under hyperglycemic conditions, a significant portion of respiratory oxygen may be lost as free radicals, contributing to NADH/NAD+ redox imbalance, protein glycation, lipid peroxidation, and the formation of inflammatory cytokines, leading to further ROS formation and mitochondrial dysfunction. In summary, the molecular mechanism linking DM and OS involves the overproduction of ROS and the impairment of the antioxidant defense system, leading to cellular dysfunction, insulin resistance, and the progression of diabetic complications through various biochemical pathways.What is the reason for weight loss of okra in room temperature?

The weight loss of okra in room temperature storage is primarily due to factors such as increased decay and senescence, leading to moisture loss and subsequent shriveling of the pods. Research indicates that okra stored at room temperature experiences higher weight loss compared to cold storage conditions. Additionally, the absence of proper packaging and insulation exacerbates weight loss, as seen in unpackaged pods stored at room temperature, which became dry and shriveled, resulting in significant weight loss. Therefore, the combination of inadequate storage conditions, lack of proper packaging, and absence of cooling measures contributes to the accelerated weight loss of okra pods when stored at room temperature.What are the potential benefits and drawbacks of using EGF and collagen cosmetics?

The use of Epidermal Growth Factor (EGF) and collagen in cosmetics offers various benefits. EGF aids in skin cell regeneration, collagen synthesis, and hyaluronic acid production, enhancing skin elasticity, moisture, and wrinkle reduction. Collagen, whether orally or topically administered, improves skin moisture, elasticity, and reduces wrinkles without reported side effects. However, challenges exist. EGF's low productivity and short half-life hinder its therapeutic application. Collagen's high molecular weight limits its skin permeability, necessitating large oral doses or suitable delivery systems for topical use. Despite these drawbacks, both EGF and collagen show promise in antiaging cosmetics, with EGF demonstrating superior skin penetration and collagen offering skin health benefits when effectively delivered.How growth medium affect the healthy and yield of citrus plants?

The choice of growth medium significantly impacts the growth and yield of citrus plants. Different mediums have been studied for their effects on citrus plants. For instance, a special seedling growth medium containing peat soil, vermiculite, and various nutrients showed high survival rates and shorter reviving times for citrus seedlings after transplanting. Additionally, potting mixes with specific compositions like sand, silt, farmyard manure, and compost have been found to enhance plant development, mineral content, and physiological variables in citrus saplings, leading to improved growth and development. Furthermore, the use of nanochitosan, biocapsules, and NPK fertilizers in the growth medium has shown to increase yield parameters like plant height, fruit weight, and fruit yield, while also maintaining qualitative parameters like TSS and acidity percentage in citrus plants. These studies highlight the critical role of growth mediums in influencing the health and productivity of citrus plants.