Who is the inventor of mitosis?
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18 Citations | There is evidence that it persists throughout the entire process of mitosis.6. |
33 Citations | It is suggested that this activity belongs to proteins responsible for the regulation of mitosis. |
These observations suggest that a common mechanism exists for mitosis in plant and animal cells. | |
286 Citations | We propose that there are other unidentified controls that regulate entry into mitosis. |
The observations described here and in Part II have implications both for the evolution of mitosis and for understanding the mitotic process generally. | |
The ability to chemically manipulate the onset of mitosis should be useful for studying the regulation of this event in mammalian cells. |
Related Questions
How does cell shape effect mitosis?5 answersCell shape has a significant impact on mitosis. Elongated cells attached to single fibers through focal adhesion clusters result in spherical mitotic cell bodies that undergo 3D displacement. Changes in cell shape during mitosis are accompanied by alterations in mechanical properties, such as increased cell surface tension and cortical stiffness. The dimensionality of the cell's microenvironment also affects mitotic spindle orientation and progression through mitosis, with circular microwells leading to greater tilting of the spindle compared to square microwells. In the absence of astral microtubules, metaphase spindles preferentially adopt a tilted position due to constraints imposed by the cell cortex in flat cells. The competition between cell shape and intercellular adhesion determines spindle orientation, with adhesion dominating when cell shape anisotropy is small and cell shape dominating when anisotropy is large.
Why is the process of mitosis important in cell division?3 answersMitosis is important in cell division because it ensures the equal distribution of genetic material to two daughter cells, maintaining genetic integrity and producing genetically identical cells. It is a highly regulated process involving complex molecular mechanisms that ensure the proper segregation of chromosomes. Mitosis also involves structural and molecular changes that can have additional effects on cell and tissue fate and shape. It plays a crucial role in tissue growth, organ development, and the maintenance of life functions. During mitosis, cells undergo extensive morphological changes, including elongation along the mitotic axis, which is necessary for successful cell division. The process of mitosis is tightly regulated and any disruption or failure can lead to abnormal cell division and potentially contribute to diseases such as cancer.
Why is mitosis important?3 answersMitosis is important because it is a key process in development and plays a critical role in maintaining tissue homeostasis. It involves deep structural and molecular changes that can have additional effects on cell and tissue fate and shape. Understanding mitosis is crucial for understanding cancer biology mechanisms and identifying potential targets for cancer treatment. Mitosis ensures the generation of genetically identical cells, which is essential for the development of organisms and their reproduction. It is also necessary for normal growth, development, and tissue repair, and is tightly regulated to ensure accurate segregation of chromosomes into each new daughter cell. In plants, mitosis is fundamental for growth and development of the plant body, as it produces two identical daughter cells that contribute to increases in length and girth in various plant organs.
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