Why inflammation happens?
Inflammation occurs as a normal physiological response to injury, infection, or other challenges to homeostasis . It is a protective mechanism that aims to eliminate the cause of damage, remove damaged cells, and initiate tissue healing and repair . Acute inflammation is a short-term, self-limiting response that helps control infections and promote wound healing . However, chronic inflammation can occur when the mission of acute inflammation is not accomplished, leading to ongoing oxidative stress and disease onset . Chronic inflammation can be caused by various factors such as persistent infection, chronic non-infectious diseases, aging, and chronic trauma . While inflammation is intended to benefit the body, an inflammatory response can go awry, resulting in collateral damage to healthy tissues and exacerbation of disease . Therefore, understanding the causes and mechanisms of inflammation is crucial for effective medical treatment and management .
Answers from top 5 papers
01 Feb 2021-Scandinavian Journal of Immunology
|Inflammation can be caused by various factors such as blood clots, immune system disorders, infections, cancers, chemical exposures, physical injuries, or neurological conditions.|
|Inflammation happens as a protective response to injury or infection, helping to eliminate the cause of injury and initiate tissue healing and repair.|
|Inflammation happens as a reaction to tissue injury and is designed to eliminate the cause of damage and promote healing.|
01 Jan 2023
|Inflammation happens as a normal physiological process to maintain homeostasis, repel foreign invaders, and initiate healing response, triggered by various environmental factors.|
|Inflammation happens as a protective response to invasion, injury, and other challenges to homeostasis, but chronic inflammation occurs when the mission is not accomplished.|