Showing papers on "Acacetin published in 1994"
TL;DR: In this paper, the composition and bacteriostatic activities of fifteen propolis samples from various botanic and geographic origins were determined, and the minimum inhibitory concentration of propolis was about 53 times higher than that reported for tetracycline againstBacillus subtilis and Staphylococcus aureus, and about 400 times higher againstEscherichia coli.
Abstract: The composition and bacteriostatic activities of fifteen propolis samples from various botanic and geographic origins were determined. Twenty-six phenolic components were identified by high-performance liquid chromatography with array photodiode detector. Acacetin and apigenin were most abundant. Pinocembrin, quercetin, rutin and vanillin were present in lesser quantities. Variance analysis shows significant differences (P≤0.05) in the contents of phenols, flavonoids and active components. The minimum inhibitory concentration of propolis is about 53 times higher than that reported for tetracycline againstBacillus subtilis andStaphylococcus aureus, and about 400 times higher againstEscherichia coli.
190 citations
TL;DR: An active anti-HIV principle, acacetin-7-O-beta-D-galactopyranoside, has been isolated from Chrysanthemum morifolium and a known flavone, chrysin, was found to be the most promising compound in this series of flavonoids.
Abstract: An active anti-HIV principle, acacetin-7-O-beta-D-galactopyranoside, has been isolated from Chrysanthemum morifolium. Seven additional flavonoids isolated from this plant, 13 known related flavonoids, and 14 synthetic flavonoids were also evaluated as inhibitors of HIV replication in H9 cells. A known flavone, chrysin, was found to be the most promising compound in this series. Flavonoids with hydroxy groups at C-5 and C-7 and with a C-2-C-3 double bond were more potent inhibitors of HIV growth. In general, the presence of substituents (hydroxyl and halogen) in the B-ring increased toxicity and/or decreased activity.
164 citations