Topic
Acacetin
About: Acacetin is a research topic. Over the lifetime, 442 publications have been published within this topic receiving 10458 citations. The topic is also known as: 5,7-Dihydroxy-2-(4-methoxyphenyl)-4-benzopyrone & Linarigenin.
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TL;DR: From the methanolic mother solntion obtained in the crystallization of acetylpectoltnarin audpectolinarin, by repeated chromatography on columns of polyamide the authors have isolated, in addition to pectolinarlgenin and linaroside, three other minor components.
Abstract: From the methanolic mother solntion obtained in the crystallization of acetylpectoltnarin audpectolinarin [1] from Linaria kurd,ca by repeated chromatography on columns of polyamide we have isolated, in addition to pectolinarlgenin and linaroside [2] three other minor components. A chloroform eluate contained the flavone aglycone (I), CleH12Os, mp 258-260°C, tool wt. 284 (mass spectrometry), NMR spectrum: doublet at 7.69 ppm, J = 8 Hz, 2 H (H-2', 6'); doublet at 6.84 ppm, J = 8 Hz; 2 H (H-3', 5'); doublet at 6.41 ppm, J = 2.5 Hz, 1 H (R-6); single, at 6.37 ppm, 1 H (H-3); doublet at 6.07 ppm, J = 2.5 Hz, 1 H (H-8); and singlet at 3.77 ppm, 3 H (CHsO group) [3].
6 citations
Journal Article•
TL;DR: In this article, the compositions, antioxidant activities and anti-tumor effects of Artemisia princeps Pampanini (APD) as well as blanched leaves (CNBD) and dried leaves (CND) from Cirsium setidens Nakai on HepG2 cells were investigated.
Abstract: In the present study, we investigated the compositions, antioxidant activities and anti-tumor effects of Artemisia princeps Pampanini (APD) as well as blanched leaves (CNBD) and dried leaves (CND) from Cirsium setidens Nakai on HepG2 cells. Water and ash contents were increased in CND. Protein and lipid contents were increased in CNBD. K, Ca, Mg, Fe and Cu contents of CND were higher than those of CNDB and APD. P contents was significantly decreased in CND. Yields of CND was reached high levels, but TPC, TFC, acacetin, apigenin, cynarin contents, and antioxidant activity were higher in APD. Viability of HepG2 liver cells was significantly decreased in APD. Therefore, extracts of APD are more effective preventing the liver cancer than extracts of CND and CNBD.
6 citations
TL;DR: Six (6) compounds are reported for the first time from this species and their structures were elucidated and identified by extensive NMR techniques, GC-MS and comparison with the previously reported literature.
6 citations
TL;DR: In this review, the protective effects of acacetin on a variety of cardiovascular diseases, as well as the existing problems and prospects, are discussed and summarized.
Abstract: Acacetin (5,7-dihydroxy-4′-methoxyflavone) is the major bioactive component of the traditional Chinese medicine “Snow lotus”. As a natural flavonoid compound, it has been shown to have good pharmacological effects such as anti-inflammatory, anticancer, and anti-obesity. Among them, its prominent role in cardiovascular diseases (CVD) has received extensive attention from scholars in recent years. In this review, the protective effects of acacetin on a variety of cardiovascular diseases, as well as the existing problems and prospects, are discussed and summarized. This review also highlights the great potential of acacetin, a natural-derived Chinese medicine, as a cardiovascular agent candidate.
6 citations
TL;DR: From present investigation, compound 1 and 7-O-β-(6″-(E)-crotonylglucopyranoside) were isolated for the first time from the genus Agastache and 1, 16, 18 and 19 in the Lamiaceae family.
6 citations