Acalypha ciliata

About: Acalypha ciliata is a research topic. Over the lifetime, 9 publications have been published within this topic receiving 135 citations.

Evaluation of the In Vitro Antiplasmodial, Antileishmanial, and Antitrypanosomal Activity of Medicinal Plants Used in Saudi and Yemeni Traditional Medicine

Abstract: The antiplasmodial, antileishmanial, and antitrypanosomal activity of twenty-five medicinal plants distributed in Saudi Arabia and Yemen was evaluated. The plants were extracted with methanol and screened in vitro against erythrocytic schizonts of Plasmodium falciparum, intracellular amastigotes of Leishmania infantum and Trypanosoma cruzi, and free trypomastigotes of T. brucei. To assess selectivity, cytotoxicity was determined on MRC-5 cells. Criteria for activity were an μg/mL and high selectivity (SI). Seven plants showed interesting antiprotozoal activity in one or more models. Extracts of Caralluma penicillata and Acalypha ciliata showed fairly good activity against P. falciparum with IC50 of 6.7 and 10.8 μg/mL and adequate selectivity ( and ). Interesting activity against L. infantum was obtained with Verbascum bottae (IC50 of 3.2 μg/mL, SI 10.2) and Solanum glabratum (IC50 8.1 μg/mL, SI 3.4). The extracts of C. penicillata, Leucas virgata, Loranthus regularis, and V. bottae exhibited moderate activity against T. brucei (IC50 8.5, 8.1, 8.3, and 2.3 μg/mL; , 7.7, 4.3, and ). These results partly support the traditional use of some of the selected medicinal plants and warrant further investigations into the putative active constituents.

Efficacy of Certain Indigenous Plant Extracts Against Seed-Borne Infection of Fusarium Moniliforme on Maize (Zea Mays L.) in South Western Nigeria

Abstract: Aqueous extracts of leaves of Ocimum gratissimum, Acalypha ciliata, Vernonia amyygdalina, Mangifera indica and Azadirachta indica were evaluated for the control Fusarium moniliforme on seeds of maize (Zea mays). The seeds were soaked sterile distilled water in 10, 20, and 30% (W/V) for 12, 24 and 48hr. All the plant extracts had significant inhibitory growth effect on the fungal pathogen. Acalypha ciliata extract was more effective than other plant extracts and compared favorably with benomyl in the control of the pathogen.

Evaluation of some aqueous plant extracts used in the control of pawpaw fruit (Carica papaya L.) rot fungi

Abstract: Objectives : To isolate, identify and establish the pathogenicity of fungi associated with post-harvest rot diseases of pawpaw fruits, and to determine the effect of various concentrations of crude extracts from the leaves of Carica papaya, Chomolaena odorata , and Acalypha ciliata on the growth of the pathogenic fungi. Methodology and results : All experiments were carried out under laboratory conditions. Fungi associated with diseased pawpaw fruits which were naturally infected and obtained from the nearby market were isolated using the blotter method and grown on Potato dextrose broth (PDB). Plant materials including Chromolaena odorata , Acalypha ciliate and Carica papaya were obtained and their ingredients extracted by slurry and filtration. Anti-fungal activities of the aqueous extracts of the leaves were determined by measuring the mycelia dry weight. The fungi isolated (and their frequency of occurrence) included Aspergillus niger (26.83%), Botryodiplodia theobromae (31.71%), Fusarium solani (39.02%) and Penicillium sp (2.44%). The results showed that all the tested concentrations (10, 20 and 30%), significantly (p<0.05) reduced the mycelial growth of the fungi in-vitro. The fungicidal effect of A. ciliata, was greater than that of Chromolaena odorata and Carica papaya . Conclusions and application of findings : The information obtained in this research could be applied in the control of fungal diseases of fruits.

Phytochemical screening, antioxidant and antimicrobial activities of Acalypha ciliata plant

Abstract: Phytochemical screening, antioxidant and antimicrobial activities of hexane, ethylacetate and methanol crude extracts of Acalypha ciliata plant was studied in this work This plant according to folk medicine has been reported to be used for treatment of female sterility, dressing of sores and schistosomiasis The preliminary screening of the various extracts was carried out using standard methods and the results revealed the presence of flavonoids, tannins, alkaloids, reducing sugar, anthraquinones, resins and glycosides The antimicrobial screening was carried out using the following organisms; Staphylococcus aureus, Eshericha coli, Bacillus subtilis, Pseudomonas aeruguinosa, Salmonella typhi, Klebsiellae pneumoniae, Candida albicans, Aspergillus niger, Penicillium notatum and Rhizopus stolonifer The free radical scavenging capacity using hydrogen peroxide was equally determined to evaluate the antioxidant activities of the extracts The result obtained showed that Acalypha ciliata extracts have interesting pharmacological active compounds and antimicrobial effects, and as such could be used in ethno medicine for treatment of bacterial infections and ailments The extracts of Acalypha ciliata plant contains notable chemical compounds that are responsible for its antioxidant and antimicrobial activity Further investigations on the chemical compositionsand possible isolation of active ingredients would be carried out

On-farm evaluation of some plant extracts as biofungicide and bioinsecticide on cowpea in Southwest Nigeria

Abstract: Aqueous extracts of leaves of Carica papaya L., Tithonia diversifolia (Hemsl) A. Gray and Acalypha ciliata Forsk were evaluated on farmers fields as potential biofungicide and bioinsecticide against the brown blotch disease and insect pests of Ife Brown variety of cowpea in year 2002 and 2003 planting seasons. All the crude extracts significantly reduced the incidence and severity of the disease, and the population of the insect pests of cowpea (P<0.01) in all the farmers’ fields. Extracts from the leaves of Carica papaya was the most effective of the botanicals and its performance was comparable to that of Benlate and Nuvacron in both disease and insect control.