Acetone

About: Acetone is a research topic. Over the lifetime, 9458 publications have been published within this topic receiving 120867 citations. The topic is also known as: propanone & dimethylketone.

Measurement and Correlation of Solubility of 7-Aminocephalosporanic Acid in Aqueous Acetone Mixtures

Abstract: Using a laser monitoring observation technique, the solubilities of 7-aminocephalosporanic acid (7-ACA) in binary acetone + water solvent mixtures were determined from 274.45 to 301.15 K, which are the important data for the operation of the crystallization process of 7-ACA from its aqueous solution. The experimental results show that the solubility of 7-ACA increases slowly with the increase of the temperature and decreases sharply with the increase of the acetone concentration. The solubility data were fitted with both the Redlich−Kister equation and the λh equation, and the correlative parameters were estimated by linear and nonlinear least-squares regression methods, respectively. It was found that the λh equation can correlate with the experimental data very well. The parameters λ, h, and Tm1 were expressed as a function of the acetone volume concentration. The solubilities of 7-ACA in water and an acetone−water mixture can be calculated by interpolation with acceptable precision for an industrial ap...

Superior Acetone Selectivity in Gas Mixtures by Catalyst-Filtered Chemoresistive Sensors.

Abstract: Acetone is a toxic air pollutant and a key breath marker for non-invasively monitoring fat metabolism. Its routine detection in realistic gas mixtures (i.e., human breath and indoor air), however, is challenging, as low-cost acetone sensors suffer from insufficient selectivity. Here, a compact detector for acetone sensing is introduced, having unprecedented selectivity (>250) over the most challenging interferants (e.g., alcohols, aldehydes, aromatics, isoprene, ammonia, H2, and CO). That way, acetone is quantified with fast response (<1 min) down to, at least, 50 parts per billion (ppb) in gas mixtures with such interferants having up to two orders of magnitude higher concentration than acetone at realistic relative humidities (RH = 30-90%). The detector consists of a catalytic packed bed (30 mg) of flame-made Al2O3 nanoparticles (120 m2 g-1) decorated with Pt nanoclusters (average size 9 nm) and a highly sensitive chemo-resistive sensor made by flame aerosol deposition and in situ annealing of nanostructured Si-doped e-WO3 (Si/WO3). Most importantly, the catalytic packed bed converts interferants continuously enabling highly selective acetone sensing even in the exhaled breath of a volunteer. The detector exhibits stable performance over, at least, 145 days at 90% RH, as validated by mass spectrometry.

Metal-organic frameworks derived hierarchical flower-like ZnO/ Co3O4 heterojunctions for ppb-level acetone detection

Abstract: The demand of acetone gas sensors with great response value and fast response/recovery time to low concentration acetone is increasing in practical diagnosis for diabetes. In this work, metal-organic frameworks (MOFs) derived flower-like ZnO/Co3O4 heterojunctions based sensor is prepared by a simple solution mixing method at room temperature. The sensor shows high acetone response value, short response/recovery time, excellent selectivity and good stability. For example, the response value of ZnO/Co3O4 heterojunctions based sensor is up to 120 % towards 500 ppb acetone at 300 ℃, which is about 30-fold enhancement than these of intrinsic ZnO and Co3O4. Moreover, its minimal detection limitation is 100 ppb acetone and it shows ultra-fast response/recovery time for ppb-level acetone (22 s/27 s@500 ppb). The excellent acetone sensing properties of flower-like ZnO/Co3O4 heterojunctions based sensor is attributed to the sharp resistance variation of heterojunction interface between ZnO and Co3O4 and the ultra-fast gas transport channel provided by ZnO nanosheets. This finding provides important insights and useful guidance for the detection of ppb-level acetone.

Determination of 14C-labelled ketone bodies by liquid-scintillation counting.

Abstract: 1. A method of assaying 14C in ketone bodies present in blood by using liquid-scintillation counting is described. 2. d(−)-β-Hydroxy[14C]butyrate is converted quantitatively into [14C]acetoacetate by means of a coupled oxidoreduction reaction involving NAD+, d(−)-β-hydroxybutyrate dehydrogenase and malic dehydrogenase in the presence of a high concentration of oxaloacetate. 3. [14C]Acetoacetate is decarboxylated to acetone and carbon dioxide which are trapped separately in a double-well flask and counted subsequently. 4. The method permits the determination of 14C activity in the individual ketone bodies and allows the activity in the carboxyl carbon atoms of acetoacetate or of d(−)-β-hydroxybutyrate to be assayed separately from the activity in the remainder of the molecule. 5. Recoveries of 14C-labelled ketone bodies added to blood approach 100% with good reproducibility in replicate analyses.