Acetonitrile

About: Acetonitrile is a research topic. Over the lifetime, 11298 publications have been published within this topic receiving 175275 citations. The topic is also known as: cyanomethane & ethyl nitrile.

Synthesis of a ligand based upon a new entry into the 3-hydroxy-N-alkyl-2(1H)-pyridinone ring system and thermodynamic evaluation of its gadolinium complex.

Abstract: The synthesis of a new, more water soluble derivative of TREN-Me-3,2-HOPO {tris[(3-hydroxy-1-methyl-2-oxo-1,2-didehydropyridine-4-carboxamido)ethyl]amine} is presented. The synthesis starts with the condensation reaction of (N-methoxyethylamino)acetonitrile hydrochloride and oxalyl chloride to give 3,5-dichloro-N-(methoxyethyl)-2(1H)-pyrazinone. The 3-position is readily substituted with a benzyloxy group, and the pyrazinone is converted to ethyl 3-(benzyloxy)-N-(methoxyethyl)-2(1H)-pyridinone-4-carboxylate by a Diels−Alder cycloaddition with ethyl propiolate. Basic deprotection of the ester followed by activation, coupling to tren, and acidic deprotection of the benzyl groups gives the ligand TREN-MOE-3,2-HOPO {tris[(3-hydroxy-1-(methoxyethyl)-2-oxo-1,2-didehydropyridine-4-carboxamido)ethyl]amine}. The gadolinium complex of TREN-MOE-3,2-HOPO was prepared by metathesis, starting from gadolinium chloride. The solubility of the new metal complex is significantly enhanced. The four protonation constants (det...

Multifunctional supramolecular self-assembly system for colorimetric detection of Hg2+, Fe3+, Cu2+ and continuous sensing of volatile acids and organic amine gases.

Abstract: A novel multifunctional gelator (1) based on an azobenzene derivative was designed and characterized. This compound could gelate some solvents including hexane, petroleum ether, DMSO, acetonitrile and ethanol through a heating–cooling procedure. The self-assembly process in different solvents was studied by means of UV-vis absorption and Fourier transform infrared (FTIR) spectra, field emission scanning electron microscopy (FESEM), rheological measurements, X-ray powder diffraction and water contact angle experiments. Interestingly, compound 1 had a high-contrast colorimetric detection ability towards Hg2+, Cu2+, Fe3+ and volatile acids and further organic amine gases in solution through its color change. At the same time, organogel 1 in acetonitrile also exhibited detection performance through a color or gel state change. In the response process, the self-assembly structures were changed from a nanofiber into a microsphere under induction by analytes. More significantly, film 1 could continuously detect volatile acids and organic amine gases. The number of cycles of film 1 for the detection of volatile acids and organic amine gases was at least seven times. The limit of detection (LOD) of film 1 towards TFA was calculated to be 0.0848 ppb. The sensing mechanisms were studied using 1HNMR, FESEM, UV-vis absorption spectra and HRMS. The intramolecular cyclization occurred on molecule 1 and a H2S molecule was lost during the detection process of Hg2+. It was proposed that the –NN– bonding could be coordinated by Fe3+ and Cu2+ and this further induced the absorption spectra and color change. For a volatile acid, it was possible that the volatile acid was combined with the N,N-dimethyl amine group of molecule 1. This research opens up a novel pathway to the fabrication of supramolecular self-assembly gels to detect polymetallic ions and trace volatile acids in the environment.