Topic
Acyl-CoA
About: Acyl-CoA is a research topic. Over the lifetime, 527 publications have been published within this topic receiving 25134 citations. The topic is also known as: Acyl Coenzyme A.
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TL;DR: Consistent with its exhibiting a function in yeast akin to that in the plant, CTS rescued the oleate growth phenotype of the pxa1 pxa2Δ mutant, and restored β-oxidation of fatty acids with a range of chain lengths and varying degrees of desaturation.
70 citations
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TL;DR: High concentrations of lactate and oxfenicine inhibit fatty acid oxidation in cardiac muscle and indicate that carnitine-acyl CoA transferase is an important site of control in the pathway of fatty acids oxidation.
70 citations
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TL;DR: The data suggest that the enzymatic activation of the peroxisome proliferating compounds is essential for their proliferating activity, but the rate of activation does not determine the potency of the proliferators.
70 citations
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TL;DR: It is proposed that the interaction of phosphatidate phosphohydrolase with the membranes that synthesize glycerolipids causes it to become metabolically active, which enables the liver to increase its capacity for triacylglycerol synthesis in response to an increased supply of fatty acids.
69 citations
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TL;DR: This study provides a mechanism for organic solvent tolerance from the point of membrane dynamics in S. cerevisiae by reporting for the first time that an increase in the synthesis of phosphatidic acid is responsible for enhanced phospholipid synthesis that confers tolerance to the organic solvent in Saccharomyces Cerevisiae.
69 citations