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Aeginetia indica

About: Aeginetia indica is a research topic. Over the lifetime, 35 publications have been published within this topic receiving 268 citations.

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Journal ArticleDOI
TL;DR: Agarwal et al. as mentioned in this paper assembled the complete chloroplast and mitochondrial genomes of Aeginetia indica, a holoparasitic plant, and showed that the two chloropslast genomes encode a similar number of proteins (except atpH) but differ greatly in length.
Abstract: Orobanchaceae have become a model group for studies on the evolution of parasitic flowering plants, and Aeginetia indica, a holoparasitic plant, is a member of this family. In this study, we assembled the complete chloroplast and mitochondrial genomes of A. indica. The chloroplast and mitochondrial genomes were 56,381 bp and 401,628 bp long, respectively. The chloroplast genome of A. indica shows massive plastid genes and the loss of one IR (inverted repeat). A comparison of the A. indica chloroplast genome sequence with that of a previous study demonstrated that the two chloroplast genomes encode a similar number of proteins (except atpH) but differ greatly in length. The A. indica mitochondrial genome has 53 genes, including 35 protein-coding genes (34 native mitochondrial genes and one chloroplast gene), 15 tRNA (11 native mitochondrial genes and four chloroplast genes) genes, and three rRNA genes. Evidence for intracellular gene transfer (IGT) and horizontal gene transfer (HGT) was obtained for plastid and mitochondrial genomes. ψndhB and ψcemA in the A. indica mitogenome were transferred from the plastid genome of A. indica. The atpH gene in the plastid of A. indica was transferred from another plastid angiosperm plastid and the atpI gene in mitogenome A. indica was transferred from a host plant like Miscanthus siensis. Cox2 (orf43) encodes proteins containing a membrane domain, making ORF (Open Reading Frame) the most likely candidate gene for CMS development in A. indica.

16 citations

Journal ArticleDOI
TL;DR: In vitro effects of AIL on various lymphoid cells found that CD4+ T cells were main producers of IL-2 and TNF upon the stimulation with ALL in vitro, while both CD4- and CD8- T cells secreted IFN and ALL was mitogenic in vitro to T enriched splenic lymphocytes as well as B enriching lymphocytes.

16 citations

Journal ArticleDOI
Jingfang Chen1, Runxian Yu1, Jin-Hong Dai1, Ying Liu1, Renchao Zhou1 
TL;DR: This study suggests the loss of photosynthesis-related functions in A. indica in both the nuclear and plastid genomes, and indicates that the photosynthesis pathway is completely lost, and that the porphyrin and chlorophyll metabolism pathway is partially retained, although chlorophyLL synthesis is not possible.
Abstract: With three origins of holoparasitism, Orobanchaceae provides an ideal system to study the evolution of holoparasitic lifestyle in plants. The evolution of holoparasitism can be revealed by plastid genome degradation and coordinated changes in the nuclear genome, since holoparasitic plants lost the capability of photosynthesis. Among the three clades with holoparasitic plants in Orobanchaceae, only Clade VI has no available plastid genome sequences for holoparasitic plants. In this study, we sequenced the plastome and transcriptome of Aeginetia indica, a holoparasitic plant in Clade VI of Orobanchaceae, to study its plastome evolution and the corresponding changes in the nuclear genome as a response of the loss of photosynthetic function. The plastome of A. indica is reduced to 86,212 bp in size, and almost all photosynthesis-related genes were lost. Massive fragments of the lost plastid genes were transferred into the mitochondrial and/or nuclear genomes. These fragments could not be detected in its transcriptomes, suggesting that they were non-functional. Most protein coding genes in the plastome showed the signal of relaxation of purifying selection. Plastome and transcriptome analyses indicated that the photosynthesis pathway is completely lost, and that the porphyrin and chlorophyll metabolism pathway is partially retained, although chlorophyll synthesis is not possible. Our study suggests the loss of photosynthesis-related functions in A. indica in both the nuclear and plastid genomes. The lost plastid genes are transferred into its nuclear and/or mitochondrial genomes, and exist in very small fragments with no expression and are thus non-functional. The Aeginetia indica plastome also provides a resource for comparative studies on the repeated evolution of holoparasitism in Orobanchaceae.

15 citations

Journal ArticleDOI
TL;DR: The results from this study demonstrated that exposure to WDDD and EDDD produced minimal changes in the activities of B cells and natural killer cells, macrophages and neutrophils, and hematological parameters were not affected.

14 citations

Patent
TL;DR: The carcinostatic agent of the present invention is an extract from seeds of Aeginetia indica and has interleukin-2 and interferon-γ inducing potency.
Abstract: The carcinostatic agent of the present invention is an extract from seeds of Aeginetia indica and has interleukin-2 and interferon-γ inducing potency. As shown in FIG. 1, all of the mice, to which this extract was not given, (Δ) died from tumor (6 mice). In contrast, in the mice, to which the extract was given by 0.6 mg/kg (□), 1.2 mg/kg (+), and 2.5 mg/kg ( ) intraperitoneally once in every two days from the day of tumor grafting, all mice showed increase in the survival rate. Thus, the extract exhibits excellent carcinostatic effect.

14 citations

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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20212
20202
20181
20141
20123
20111