Topic
Aging brain
About: Aging brain is a research topic. Over the lifetime, 1255 publications have been published within this topic receiving 66405 citations.
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01 Nov 1978
TL;DR: The concept that aging is an endogenous process inherent in all living things and not basically dependent on stress and disease is increasingly accepted, although there are still not sufficient data to choose finally between these alternatives or to conclude that a cell, organ, or organism placed in an optimal environment may not live indefinitely.
Abstract: I * Introduction.- 1 The Ponce de Leon Trail Today.- II * Aging in Cells and their Molecules.- 2 Cell Aging: A Model System Approach.- 3 Is Limited Cell Proliferation the Clock That Times Aging?.- 4 Molecular Biology of Aging.- III * Aging in Plants and Lower Animals.- 5 Cellular and Metabolic Aspects of Senescence in Higher Plants.- 6 The Biological Significance of Death in Plants.- 7 Aging in Lower Animals.- IV * Aging in Humans and Other Mammals.- 8 Exercise and Aging.- 9 Diet and Nutrient Needs in Old Age.- 10 Nutritional Regulation of Longevity.- 11 Consequences of Alcohol and Other Drug Use in the Aged.- 12 Physical Changes of the Aging Brain.- 13 Aging and Immune function.- 14 Genes and Aging.- 15 The Dilemma of Aging Parents: Increased Risk of Genetically Abnormal Offspring.- V * Hormones and Aging.- 16 Endocrinology and Aging.- 17 Hormone "Replacement" in the Aged: Proceed with Care.- 18 Altered Biochemical Responsiveness and Hormone Receptor Changes during Aging.- 19 The Brain and Aging.- VI * Aging in Perspective.- 20 Evolutionary Biology of Senescence.- 21 The Origin, Evolution, Nature, and Causes of Aging.
18 citations
TL;DR: The colocalization of structural and functional MRI correspondents of visuospatial associative test performance within medial-temporal regions validates multimodal imaging in describing behaviorally relevant variability in the aging brain and suggests that the Placing Test has the potential for detecting early cognitive changes occurring in preclinical phases of Alzheimer's disease.
18 citations
TL;DR: Enfin, certains mecanismes compensatoires semblent etre sous-tendus par le cortex frontal dans les de two cas, mais des etudes restent a faire pour specifier quelles parties of cette vaste region sont impliquees.
18 citations
TL;DR: Treatment of hypertension may prevent cognitive decline and dementia, but methodological issues have limited the ability of randomized clinical trials to show this conclusively.
18 citations
01 Jan 2007
18 citations