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Showing papers on "Aldose published in 1972"


Book ChapterDOI
01 Jan 1972
TL;DR: This chapter discusses the use of gas–liquid chromatography (GLC) for the preparation of alditol acetates, an efficient and accurate method for the quantitative analysis of a Aldoses in biological materials.
Abstract: Publisher Summary This chapter discusses the use of gas–liquid chromatography (GLC) for the preparation of alditol acetates. Analysis of alditol acetates by GLC is an efficient and accurate method for the quantitative analysis of aldoses in biological materials. The alditol acetate method is used to determine aldoses in several biological materials such as oligosaccharides, polysaccharides, and glycoproteins. The response factor is determined for each aldose by repeating the alditol acetate procedure, including the hydrolysis step with known aldoses and comparing the weight to area ratio of the aldose to that of the internal standard. Response factors obtained in this manner are corrected for hydrolytic losses.

112 citations


Patent
21 Mar 1972
TL;DR: In this paper, the authors present a method for manufacturing keto-sugars from ALDOSE SUGARS by heating a solution of the mixture of the two in the presence of an ALKALI or ALkaline EARTH ALUMINATE CATALYST.
Abstract: THE INVENTION IS DIRECTED TO A METHOD FOR MANUFACTURE OF KETOSE SUGARS FROM ALDOSE SUGARS BY HEATING A SOLUTION OF THE ALDOSE SUGAR IN THE PRESENCE OF AN ALKALI OR ALKALINE EARTH ALUMINATE CATALYST SO AS TO CONVERT THE ALDOSE SUGAR TO A KETOSE SUGAR IN HIGH YIELDS. THEREAFTER, THE KETOSE SUGAR IS RECOVERED FROM THE REACTION MIXTURE BY TREATMENT WITH A SUITABLE AGENT.

8 citations


Patent
30 Oct 1972
TL;DR: In this article, the authors proposed a method for the manufacturing of keto-sugars from ALDOSE SUGARS, adding an ALKALI or ALKaline EARTH ALUMINATE CATalyst to the solution to provide a reaction mixture.
Abstract: 1. IN A METHOD FOR THE MANUFACTURE OF KETOSE SUGARS FROM ALDOSE SUGARS COMPRISING PROVIDING A SOLUTION OF ALDOSE SUGAR, ADDING AN ALKALI OR ALKALINE EARTH ALUMINATE CATALYST TO SAID SOLUTION TO PROVIDE A REACTION MIXTURE, MAINTAINING SAID REACTION MIXTURE AT A TEMPERATURE SUFFICIENT TO SUBSTANTIALLY CONVERT THE ALDOSE SUGAR TO KETOSE SUGAR, ADJUSTING THE PH OF SAID REACTION MIXTURE TO WITHIN THE RANGE OF 6 TO 8 SO AS TO PRECIPITATE AND SAID ALUMINATE MOIETY OF SAID ALUMINATE CATALYST AND PROVIDE A REACTION MIXTURE CONTAINING AN ALUMINUM HYDROXIDE PRECIPITATE IN A SUGAR SOLUTION, THE IMPROVEMENT COMPRISING CONTROLLING THE CONCENTRATION OF SAID ALUMINUM HYDROXIDE IN SAID REACTION MIXTURE AT A LEVEL OF LESS THAN ABOUT 8 PERCENT BY WEIGHT, PROVIDING A FLOWING STREAM OF SAID REACTION MIXTURE, MOVING SAID FLOWING STREAM OF SAID REACTION MIXTURE AT A FLOW RATE OF AT LEAST ABOUT 1 FOOT PER SECOND IN A DIRECTION SUBSTANTIALLY PARALLEL TO A MEMBRANE WHILE MAINTAINING A PRESSURE DIFFERENTIAL OF FROM ABOUT 2 P.S.I.G. TO ABOUT 2,000 P.S.I.G. ACROSS SAID MEMBRANE DURING SAID MOVEMENT OF SAID REACTION MIXTURE AND TRANSFERRING SAID SUGAR SOLUTION THROUGH SAID MEMBRANE.

6 citations


Journal ArticleDOI
TL;DR: In this paper, the reaction whereby aldose or ketose precursors are converted in acidified aqueous ethanol in the presence of p -toluidine into 3-deoxyaldos-2-uloses and the latter are trapped as the crystalline bis(benzoylhydrazones) is shown to be of wide generality.

5 citations


Book ChapterDOI
01 Jan 1972
TL;DR: In this article, the synthesis of a ketose from a partially benzylated aldose is discussed, in which the reducing carbon atom represents C-4 or C-5 in the original aldoses.
Abstract: Publisher Summary This chapter discusses the synthesis of a ketose from a partially benzylated aldose. Aldopyranoses and aldofuranoses that are fully benzylated except at C-1 and at the other carbon atom involved in the hemiacetal ring (C-4 or C-5) are readily accessible through the benzylation and subsequent hydrolysis of aldosides; the preparation of 2,3,4,6-tetra-O-benzyl-α- d -glucopyranose. Such benzylated aldoses are readily reduced to the corresponding partially benzylated alditols through the action of sodium borohydride or lithium aluminum hydride. Selective blocking of the primary hydroxyl group in such substituted alditols leaves only the secondary hydroxyl group available for oxidative attack; removal of the masking groups subsequent to oxidation gives a ketose in which the reducing carbon atom represents C-4 or C-5 in the original aldose.