Topic
Aldose
About: Aldose is a research topic. Over the lifetime, 1270 publications have been published within this topic receiving 27197 citations. The topic is also known as: aldoses.
Papers published on a yearly basis
Papers
More filters
••
TL;DR: Synthese d'acide N-acetyl O-[tetra-O-benzyl-2,3,4,6 hexopyranosyl] acetohydroxamique a partir d'O-phtalimido-1 tri-O-, 3,5 ribofuranose, d'hydrazine et d'anhydride d'Acide acetique
5 citations
••
TL;DR: In this paper, simple routes to the title epoxide, using carbonate esters of methyl 4,6-O -benzylidene-α- d -glucopyranoside, are described.
5 citations
•
28 Dec 2005
TL;DR: In this article, a process for 5-deoxy-L-arabinose is described, which is used as a raw material for the production of sapropterin, a therapeutic agent for atypical hyperphenylalaninemia.
Abstract: The present invention provides a process capable of industrially producing 5-deoxy-L-arabinose, important as a raw material for the production of sapropterin useful as a therapeutic agent for atypical hyperphenylalaninemia, satisfactorily efficiently even with a simple production apparatus. Provided is the process for producing 5-deoxy-L-arabinose characterized by including: reacting L-rhamnose with a C 11-16 straight chain alkyl mercaptan compound in the presence of an acid catalyst to prepare L-rhamnose dialkylmercaptal; subjecting then the obtained compound to an oxidation reaction to prepare a sulfonyl derivative; and subjecting then the sulfonyl derivative to a carbon-reduction reaction to prepare 5-deoxy-L-arabinose. The present production process can also be applied to a process for producing compounds obtained by removing one carbon atom from other aldol compounds, and thus the present invention provides a general process for producing compounds obtained by reducing the number of carbon atoms from aldose compounds.
5 citations
••
TL;DR: In this article, a series of 1-phenyl-3-methyl-5-pyrazolone (PMP) aldose was eluted on a C18 column with an acetonitrile-phosphate buffer over the range of pH 2-10 in reversed phase liquid chromatography.
5 citations