Topic
Aldose
About: Aldose is a research topic. Over the lifetime, 1270 publications have been published within this topic receiving 27197 citations. The topic is also known as: aldoses.
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TL;DR: In this paper, the acid-catalyzed rearrangements of terminal mono-O -isopropylidene derivatives of some aldose diethyl dithioacetals in N,N -dimethylformamide have been studied.
3 citations
3 citations
Patent•
13 Jul 2018
TL;DR: In this article, a method for preparing sedoheptulose and aldose in the immobilized enzyme cascade reaction is described, which is high in preparation efficiency and cheap in raw materials, and is applicable to large scale industrial production.
Abstract: The invention relates to a preparation method of sedoheptulose and aldose in an immobilized enzyme cascade reaction, and specifically discloses a method for preparing sedoheptulose and aldose in the immobilized enzyme cascade reaction. The method comprises the following steps: taking L-erythrulose and 1,3-dioxyacetone as starting materials, and preparing D-sedoheptulose-7-phosphoric acid by usinga one-pot method of immobilized kinase EK, immobilized isomerase TRI, erythrulose phosphoric acid isomerase RPI, immobilized aldolase FSA and immobilized ATP regenerated enzyme PPK; and further generating sedoheptulose and aldose. The method is high in preparation efficiency and cheap in raw materials, and is applicable to large-scale industrial production, so that the preparation cost is greatlyreduced.
3 citations
TL;DR: The solubility of deoxycholyl 2-deoxyglucuronide in an aqueous solution was sufficient under physiological conditions, and the desired material reacted with model peptides to produce covalently bound adducts only via the transacylation mechanism.
Abstract: Acyl glucuronides, which are biosynthesized by the action of glucuronosyltransferases to material for detoxification, are water-soluble and chemically active; they produce irreversible protein adducts via both the transacylation mechanism and the imine mechanism. The acyl group at the C-1 position migrates from the anomeric carbon to the C-2 position of the glucuronic acid moiety, producing the aldehyde group at the C-1 position, where the protein easily condenses through a Schiff's base, in the open-chain aldose form. The elimination of the hydroxyl group at the C-2 position therefore may prevent a protein-bound adduct via the imine mechanism. In this paper, we describe the synthesis and characterization of an acyl 2-deoxyglucuronide of deoxycholic acid as a model compound to investigate its possible utility as a water-soluble affinity labeling reagent for lipophilic carboxylic acids. The solubility of deoxycholyl 2-deoxyglucuronide in an aqueous solution was sufficient under physiological conditions, and the desired material reacted with model peptides to produce covalently bound adducts only via the transacylation mechanism.
3 citations
Patent•
26 Sep 2001
TL;DR: In this article, a carboxylic acid type saccharide derivative is represented by the general formula G-NHCO-(CH2)n-COOH (G is an aldose residue after removal of a reducing terminal hydroxyl group and the whole hyroxyl groups existing in the residue are protected; n is an integer of 6-20).
Abstract: PROBLEM TO BE SOLVED: To obtain a glycolipid usable in a wide range as various kinds of functional materials by forming a stable molecular aggregate excellently dispersible in water from a readily obtainable raw material. SOLUTION: This carboxylic acid type saccharide derivative is represented by the general formula G-NHCO-(CH2)n-COOH (G is an aldose residue after removal of a reducing terminal hydroxyl group and the whole hydroxyl groups existing in the residue are protected; n is an integer of 6-20).
3 citations