Aldose

About: Aldose is a research topic. Over the lifetime, 1270 publications have been published within this topic receiving 27197 citations. The topic is also known as: aldoses.

Synthesis of 1-deoxy-1-[(4-quinazolon-3-yl) amino/methyl-amino-d-fructose as cns active compounds.

Abstract: A new series of 4-quinazolone i.e. 1-deoxy-1-(alpha-substituted-3-amino/methylamino-4-quinazolono)-D-fruc tose have been synthesized by refluxing oxalate salt of 3-amino-4-quinazolone and anhydrous D-glucose, with a view to observe the effect of aldose and amines linkage on central nervous system. The compounds were tested on albino mice of both sex. Some of them showed CNS depressant effect.

Biodegradable copolymers derived from sugar-based hydroxy acids

Abstract: Biodegradable copolymers containing groups of formula (I) derived from an aldose or ketose and groups of formula (II) derived from a hydroxy acid. Copolymers containing 1 - 99% of groups of formula (I) --O-CH(R)-CO-X-CO-- and at least 1% of groups of formula (II) --O-L-CO-- R = the residue of an acid R-CHOH-COOH derived from an ose, the functional groups in R optionally being substituted;X = -C(R1)(R2)- or -C(R1)(R2)-C(R3)(R4)-;R1, R2, R3, R4 = H, alkyl, allyl, aryl, or aralkyl;L = the residue of a hydroxy acid HO-L-COOH selected from those capable of forming a dilactone or monolactone ring Copolymers in which the group R is derived from an aldonic, uronic, or erythronic acid are preferred, especially those where L is derived from an aldonic, 5-hydroxy pentanoic or 6-hydroxy hexanoic acid.