Topic
Aldose
About: Aldose is a research topic. Over the lifetime, 1270 publications have been published within this topic receiving 27197 citations. The topic is also known as: aldoses.
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Journal Article•
TL;DR: The conditional,product and mechanism of Bormine Water oxidating Aldose and Ketose are discussed and the best distinguishing method is given.
Abstract: The conditional,product and mechanism of Bormine Water oxidating Aldose and Ketose are discussed in this paper.The results show: in the acid solution which pH is 2～3,Bormina Water can distinguish Glucose and Fructose;in the nearly neutral solution which pH is 5～6 and in the Alkalescence solution which pH is 9～10.Bormina Water can not distinguish Glucose and Fructose;Further more the best distinguishing method is given.
1 citations
1 citations
Patent•
26 Mar 2007TL;DR: In this paper, the authors proposed a thermostable L-ribose isomerase with MW. 32,000 (by SDS-PAGE), optimal temperature of 45°C, optimal pH of pH 9.0 (glycine-NaOH buffer), and stable physicochemical properties such as temperature stability up to 45° C.
Abstract: Object: To provide a thermostable L-ribose isomerase. Means for Resolution: The thermostable L-ribose isomerase with MW. 32,000 (by SDS-PAGE), optimal temperature of 45° C., optimal pH of pH 9.0 (glycine-NaOH buffer), and stable physicochemical properties such as temperature stability up to 45° C. during thermal treatment at pH 9.0 for 10 minutes, and with an action to isomerize L-ribose to generate L-ribulose or of inversely to isomerize L-ribulose to generate L-ribose. A conversion method between an aldose and a ketose comprising allowing the thermostable L-ribose isomerase as an enzyme derived from (1) Raoultella ornithinolytica strain MB426 (NITE BP-277) to interact with an aldose selected from L-ribose, D-lyxose, D-tallose, D-mannose, L-allose and L-gulose to isomerize the aldose to generate a ketose selected from the individually corresponding L-ribulose, D-xylulose, D-tagatose, D-fructose, L-psicose and L-sorbose or to interact with a ketose selected from L-ribulose, D-xylulose, D-tagatose, D-fructose, L-psicose and L-sorbose to isomerize the ketose to generate an aldose selected from the individually corresponding L-ribose, D-lyxose, D-tallose, D-mannose, L-allose and L-gulose.
1 citations
Patent•
15 Sep 2010
TL;DR: In this paper, a color development method for phosphate ions contained in an inspection water was proposed, which includes a step in which a first water solution containing hexaammonium heptamolybdate or alkali metal salts of molyb date, an antimony compound with a valence of antimony of 3 such as tartrate antimonylcalium and sulfate and a second water solution including saccharide compounds selected from the group of monosaccharides such as aldose with carbon number of 5, aldoses with carbon numbers of
Abstract: PROBLEM TO BE SOLVED: To develop the color of phosphate ions contained in an inspection water through generation of molybdenum blue by means of an agent which can be stored.SOLUTION: A color development method for phosphate ions contained in an inspection water includes a step in which a first water solution containing hexaammonium heptamolybdate or alkali metal salts of molybdate, an antimony compound with a valence of antimony of 3 such as tartrate antimonylcalium and sulfate and a second water solution including saccharide compounds selected from the group of monosaccharide compounds such as aldose with carbon number of 5, aldose with carbon number of 6, ketose with carbon number of 6 and oligosaccharide or glycoside which can produce one of these monosaccharides through decomposition are added to inspection water and a step in which the inspection water to which the first water solution and the second water solution are added is heated to 60°C or more.
1 citations
TL;DR: In this article , a series of six rhodanine based inhibitors of aldose reductase was designed, synthesized, and tested for their ability to inhibit aldos reductases and for selectivity relative to structurally related aldehydes.
Abstract: Aldose reductase, the first enzyme of the polyol pathway represents a key drug target in therapy of diabetic complications. In this study a series of six novel rhodanine based inhibitors of aldose reductase was designed, synthesized, and tested for their ability to inhibit aldose reductase and for selectivity relative to structurally related aldehyde reductase. Aldose reductase inhibitory activities of the compounds were characterized by the IC50 values ranging from 2000 nM to 20 nM. The values of selectivity factors relative to aldehyde reductase were decreasing in the same array from 24 to 5. In silico docking into the inhibitor binding site of aldose reductase revealed a specific binding pattern of the compounds comprising interaction of the deprotonated 4-hydroxybenzylidene group with the anion-binding sub-pocket of aldose reductase, creating a strong H-bond and charge interactions. Predicted pH-distribution profiles of the novel compounds into octanol, supported by experimentally determined distribution ratios, favour drug uptake at the physiological pH, as a result of the presence of the low-acidic phenolic group, instead of the more acidic carboxymethyl functional group.
1 citations