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Aldose

About: Aldose is a research topic. Over the lifetime, 1270 publications have been published within this topic receiving 27197 citations. The topic is also known as: aldoses.


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01 Jan 1998
TL;DR: Two different enzymatic systems were successfully employed for the continuous regeneration of the coenzyme necessary in this reaction to produce D-fructose essentially free of D-glucose by this simple and convenient method.
Abstract: In the Cetus process crystalline D-fructose is produced from D-glucose via the intermediate 2-keto-~-glucose. the first step in the traditional process is catalyzed by the immobilized enzyme pyranose 2-oxidase, the ensuing reduction is performed by catalytic hydrogenation. In an entirely enzymatic variation of this process, soluble pyranose 2-oxidase from Trurnetes rnulficolor was employed. This biocatalyst could be efficiently stabilized under operational conditions by the addition of bovine serum albumin (BSA) together with catalase which decomposes hydrogen peroxide formed as a by-product. D-Glucose could be converted into 2keto-D-glucose in yields above 98%. When the biocatalyst together with both stabilizing agents was separated from the product solution by ultrafiltration, it could be reutilized for several subsequent batch operation cycles. 2-Keto-D-glucose thus obtained was quantitatively reduced to D-fructose by NAD(P)-dependent aldose reductase from Candidu tenuis. Two different enzymatic systems were successfully employed for the continuous regeneration of the coenzyme necessary in this reaction. In this way, D-fructose essentially free of D-glucose can be prepared by this simple and convenient method.
Patent
12 Dec 2017
TL;DR: In this article, a method for simultaneously detecting uronic acid and aldose by utilizing a gas chromatography-mass spectrometry method is presented. But the method is not suitable for the detection of polysaccharides.
Abstract: The invention discloses a method for simultaneously detecting uronic acid and aldose by utilizing a gas chromatography-mass spectrometry method. The method comprises the following steps: performing silicon etherification derivation on samples and monosaccharides in a mixed monosaccharide standard solution through a sodium borohydride reduced-hexamethyldisilazane-trimethylsilane system to prepare silicon etherification products of sugar alcohol and 6-carboxyl-sugar alcohol, detecting reaction products through the gas chromatography-mass spectrometry method (GC-MS), taking a ratio of the peak areas of the mixed monosaccharide standard solution with different concentrations to the internal standard peak area as a vertical coordinate, taking the concentration of each monosaccharide, establishing a standard curve, and quantifying the content of the uronic acid, aldose and other monosaccharides in the sample solution by using an internal standard method. The method is simple, convenient, rapid and accurate, can be applied to detecting and analyzing the monosaccharide composition in traditional Chinese medicine saponin and traditional Chinese medicine polysaccharides, and is high in specificity, high in repeatability, high in separation degree and reliable in results.
Journal ArticleDOI
TL;DR: The D-ribose or D-erythrose derived acyclic synthon, which possesses a 2-malonyl carbon chain at C-1 position, was cyclized stereoselectively to a six or five-membered carbocycle as mentioned in this paper.
Abstract: The D-ribose or D-erythrose derived acyclic synthon, which possesses a 2-malonyl carbon chain at C-1 position, was cyclized stereoselectively to a six- or five-membered carbocycle. Those carbocycles were converted into pseudo-β-L-mannopyranose derivatives or pseudo-β-L-arabinofuranose derivatives efficeintly.
Book ChapterDOI
TL;DR: Aldose reduct enzyme and aldehyde reductase are members of a broad family of NADPH-dependent reductases that reduce aldose sugars to their respective sugar alcohols while aldehydes reduces a broad range of aromatic and aliphatic aldeHydes.
Abstract: Aldose reductase (EC 1.1.1.21) and aldehyde reductase (EC 1.1.1.2) are members of a broad family of NADPH-dependent reductases (Feldstead and Bachur, 1980). While the physiological role of either enzyme remains unknown, it is generally assumed that aldose reductase reduces aldose sugars to their respective sugar alcohols while aldehyde reductase reduces a broad range of aromatic and aliphatic aldehydes. Aldehyde reductase is also known as hexonate dehydrogenase EC 1.1.1.19) because of its ability to oxidize L-gulonic acid to glucuronic acid..
Journal ArticleDOI
TL;DR: In this article, a reducing trisaccharide named ristriose was synthesized in twenty one steps, starting from D-glucose, D-mannose and D-arabinose, with an overall yield of 3.5 %.

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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
20233
20226
20213
20207
20196
201813