Topic
Alkylation
About: Alkylation is a research topic. Over the lifetime, 29915 publications have been published within this topic receiving 464944 citations. The topic is also known as: alkylation reaction.
Papers published on a yearly basis
Papers
More filters
TL;DR: Many methods have been developed for the enantio-and diastereoselective synthesis of α,α-disubstituted α-amino acids, many of which are focused on the total synthesis of natural products and related bioactive compounds as mentioned in this paper.
268 citations
TL;DR: In this paper, a benzene alkylation with ethene and propene has been carried out under liquid phase reaction conditions over zeolites MCM-22, Beta, and ZSM-5.
267 citations
TL;DR: The first general and highly enantioselective organocatalytic Friedel−Crafts alkylation of indoles with simple α,β-unsaturated ketones has been accomplished and a new catalyst amine salt is identified that exhibits high reactivity and selectivity for iminium ion catalysis.
267 citations
TL;DR: Very high enantioselectivity has been achieved both in the copper-catalystzed alkylation of allylic substrates by Grignard and organozinc reagents and in the iridium-catalyzed amination of cinnamyl carbonate by employing a very efficient phosphoramidite ligand.
Abstract: Very high enantioselectivity has been achieved both in the copper-catalyzed alkylation of allylic substrates by Grignard and organozinc reagents and in the iridium-catalyzed amination of cinnamyl carbonate by employing a very efficient phosphoramidite ligand
265 citations
265 citations