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Aloe vera

About: Aloe vera is a research topic. Over the lifetime, 3936 publications have been published within this topic receiving 56304 citations.


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Journal ArticleDOI
TL;DR: The aim of this review is to further highlight recently discovered effects and applications of the leaf gel of A. vera to enhance the intestinal absorption and bioavailability of co-administered compounds as well as enhancement of skin permeation.
Abstract: Many of the health benefits associated with Aloe vera have been attributed to the polysaccharides contained in the gel of the leaves. These biological activities include promotion of wound healing, antifungal activity, hypoglycemic or antidiabetic effects antiinflammatory, anticancer, immunomodulatory and gastroprotective properties. While the known biological activities of A. vera will be briefly discussed, it is the aim of this review to further highlight recently discovered effects and applications of the leaf gel. These effects include the potential of whole leaf or inner fillet gel liquid preparations of A. vera to enhance the intestinal absorption and bioavailability of co-administered compounds as well as enhancement of skin permeation. In addition, important pharmaceutical applications such as the use of the dried A. vera gel powder as an excipient in sustained release pharmaceutical dosage forms will be outlined.

889 citations

Journal ArticleDOI
TL;DR: Research since the 1986 review has largely upheld the therapeutic claims made in the earlier papers and indeed extended them into other areas and a common theme running though much recent research is the immunomodulatory properties of the gel polysaccharides, especially the acetylated mannans from Aloe vera, which are now a proprietary substance covered by many patents.

815 citations

Journal ArticleDOI
Kojo Eshun1, Qian He1
TL;DR: Chemical analysis reveals that Aloe vera contains various carbohydrate polymers, notably glucomannans, along with a range of other organic and inorganic components.
Abstract: Scientific investigations on Aloe vera have gained more attention over the last several decades due to its reputable medicinal properties. Some publications have appeared in reputable Scientific Journals that have made appreciable contributions to the discovery of the functions and utilizations of Aloe--"nature's gift." Chemical analysis reveals that Aloe vera contains various carbohydrate polymers, notably glucomannans, along with a range of other organic and inorganic components. Although many physiological properties of Aloe vera have been described, it still remains uncertain as to which of the component(s) is responsible for these physiological properties. Further research needs to be done to unravel the myth surrounding the biological activities and the functional properties of A. vera. Appropriate processing techniques should be employed during the stabilization of the gel in order to affect and extend its field of utilization.

605 citations

Journal ArticleDOI
TL;DR: The aloe vera plant, its properties, mechanism of action and clinical uses are briefly reviewed in this article.
Abstract: Aloe vera is a natural product that is now a day frequently used in the field of cosmetology. Though there are various indications for its use, controlled trials are needed to determine its real efficacy. The aloe vera plant, its properties, mechanism of action and clinical uses are briefly reviewed in this article.

577 citations

Journal ArticleDOI
TL;DR: A review of the botany, physical and chemical properties, and biological activities of the Aloe vera plant finds that it contains multiple constituents with potential biological and toxicological activities, yet the active components elude definition.
Abstract: Aloe barbadensis (Miller), Aloe vera, has a long history of use as a topical and oral therapeutic. The plant is the source of two products, gel and latex, which are obtained from its fleshy leaves. Aloe vera products contain multiple constituents with potential biological and toxicological activities, yet the active components elude definition. Ingestion of Aloe vera is associated with diarrhea, electrolyte imbalance, kidney dysfunction, and conventional drug interactions; episodes of contact dermatitis, erythema, and phototoxicity have been reported from topical applications. This review examines the botany, physical and chemical properties, and biological activities of the Aloe vera plant.

542 citations


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Performance
Metrics
No. of papers in the topic in previous years
YearPapers
2023306
2022640
2021273
2020293
2019268
2018279