Showing papers on "Ammonium tetrathiomolybdate published in 2017"

Ammonium tetrathiomolybdate following ischemia/reperfusion injury: Chemistry, pharmacology, and impact of a new class of sulfide donor in preclinical injury models

Abstract: Background: Early revascularization of ischemic organs is key to improving outcomes, yet consequent reperfusion injury may be harmful. Reperfusion injury is largely attributed to excess mitochondrial production of reactive oxygen species (ROS). Sulfide inhibits mitochondria and reduces ROS production. Ammonium tetrathiomolybdate (ATTM), a copper chelator, releases sulfide in a controlled and novel manner, and may offer potential therapeutic utility. Methods and findings: In vitro, ATTM releases sulfide in a time-, pH-, temperature-, and thiol-dependent manner. Controlled sulfide release from ATTM reduces metabolism (measured as oxygen consumption) both in vivo in awake rats and ex vivo in skeletal muscle tissue, with a superior safety profile compared to standard sulfide generators. Given intravenously at reperfusion/resuscitation to rats, ATTM significantly reduced infarct size following either myocardial or cerebral ischemia, and conferred survival benefit following severe hemorrhage. Mechanistic studies (in vitro anoxia/reoxygenation) demonstrated a mitochondrial site of action (decreased MitoSOX fluorescence), where the majority of damaging ROS is produced. Conclusions: The inorganic thiometallate ATTM represents a new class of sulfide-releasing drugs. Our findings provide impetus for further investigation of this compound as a novel adjunct therapy for reperfusion injury.

Facile Solution Synthesis of Tungsten Trioxide Doped with Nanocrystalline Molybdenum Trioxide for Electrochromic Devices

Abstract: A facile, highly efficient approach to obtain molybdenum trioxide (MoO3)-doped tungsten trioxide (WO3) is reported. An annealing process was used to transform ammonium tetrathiotungstate [(NH4)2WS4] to WO3 in the presence of oxygen. Ammonium tetrathiomolybdate [(NH4)2MoS4] was used as a dopant to improve the film for use in an electrochromic (EC) cell. (NH4)2MoS4 at different concentrations (10, 20, 30, and 40 mM) was added to the (NH4)2WS4 precursor by sonication and the samples were annealed at 500 °C in air. Raman, X-ray diffraction, and X-ray photoelectron spectroscopy measurements confirmed that the (NH4)2WS4 precursor decomposed to WO3 and the (NH4)2MoS4–(NH4)2WS4 precursor was transformed to MoO3-doped WO3 after annealing at 500 °C. It is shown that the MoO3-doped WO3 film is more uniform and porous than pure WO3, confirming the doping quality and the privileges of the proposed method. The optimal MoO3-doped WO3 used as an EC layer exhibited a high coloration efficiency of 128.1 cm2/C, which is larger than that of pure WO3 (74.5 cm2/C). Therefore, MoO3-doped WO3 synthesized by the reported method is a promising candidate for high-efficiency and low-cost smart windows.

Molybdenum disulfide nano-catalyst preparation method, catalyst and application thereof

Abstract: The invention discloses a molybdenum disulfide nano-catalyst preparation method and catalyst which can be applied to a catalytic hydrogenation process of heavy oil According to the preparation method disclosed by the invention, ammonium tetrathiomolybdate is utilized as a raw material and a surface active agent, the ammonium tetrathiomolybdate is dissolved into absolute methanol, then a reducing agent is added after the ammonium tetrathiomolybdate is mixed evenly, and the ammonium tetrathiomolybdate is put into a constant-temperature oven of 100 to 250 DEG C to be stored for 3 to 48 hours; the molybdenum disulfide nano-catalyst can be obtained after separation The molybdenum disulfide nano-catalyst prepared through the invention has smaller size and uniform particle size The molybdenum disulfide nano-catalyst prepared through the invention has a larger contact angle so as to have better dispersion in organic solvent, and catalytic performance of the molybdenum disulfide nano-catalyst in a catalytic process can be improved According to the research, the MoS2 nano-catalyst is applied to the catalytic hydrogenation process of heavy oil for the first time Furthermore, the preparation method disclosed by the invention is simple to operate, has moderate condition, low cost and a simple synthesizing device and can be hopefully applied to industrial production

Preparation method of two-dimensional MoS2 nano layer for producing H2 by defect induction high photocatalysis

Abstract: The invention relates to a preparation method of a two-dimensional MoS2 nano layer catalyst under different preparation conditions. An MoS2 monomer is prepared through an ammonium tetrathiomolybdate and N,N-dimethyl formamide (DMF) hydrothermal method. The two-dimensional MoS2 nano layer photocatalyst has excellent photocatalytic property, can quickly prepare hydrogen gas under the conditions of normal temperature, normal pressure and illumination, and has a lasting photocatalytic activity. The photocatalyst prepared at different temperatures is cheap and efficient.

Hollow molybdenum disulfide/molybdenum trioxide flower-like spherical heterostructure nano material, preparation method and application

Abstract: The invention relates to a preparation method for a hollow molybdenum disulfide/molybdenum trioxide flower-like spherical heterostructure nano material. The preparation method comprises the following steps: 1) dispersing ammonium tetrathiomolybdate, urea and hydrazine hydrate into N,N-dimethyl formamide so as to form a homogeneous solution; 2) transferring the solution obtained in the step 1) into a reaction kettle, and performing reaction for 8-10 hours at 160-240 DEG C; 3) after the reaction is completed, naturally cooling to the room temperature, performing solid-liquid separation, and washing and drying precipitate, thereby obtaining the hollow MoS2/MoO3 flower-like spherical heterostructure nano material. By adopting the hollow MoS2/MoO3 flower-like spherical heterostructure nano material provided by the invention, the hydrogen evolution(HER) performance of a catalyst is remarkably improved.

Large-area molybdenum disulfide-based fiber sensing probe and preparation method thereof

Abstract: The invention discloses a large-area molybdenum disulfide-based fiber sensing probe and a preparation method thereof. The method comprises the following steps of coating the surface of a sensing area of an optical fiber with an ammonium tetrathiomolybdate solution, and preparing a molybdenum disulfide nano-film on the surface of the sensing area of the optical fiber by adopting an ammonium tetrathiomolybdate thermal decomposition method, wherein the area of the molybdenum disulfide nano-film is 500-1,000mm . According to the prepared fiber sensing probe, molybdenum disulfide nanoparticles directly grow on the surface of the sensing area of the optical fiber, the molybdenum disulfide is in tight contact with the surface of the sensing area of the optical fiber, so that the damage to a molybdenum disulfide layer in the transfer process is avoided and the detection stability and sensitivity of the fiber sensor probe are improved.

Molybdenum trioxide nanofiber preparation method based on macromolecule form board

Abstract: The invention provides a molybdenum trioxide nanofiber preparation method based on a macromolecule form board. A nanofiber thin film loading ammonium tetrathiomolybdate is used as the form board, molybdenum trioxide powder is used as a growth source, and a physical vapor deposition method is used for preparing molybdenum trioxide nanofibers. In addition, according to the preparation method, organic materials serve as the form board, the molybdenum trioxide nanofibers with the uniform morphology are further prepared, the organic materials and inorganic materials are well combined together, and specific morphology structures are efficiently prepared. The molybdenum trioxide nanofiber preparation method is simple and practical. In addition, absorption of the obtained molybdenum trioxide nanofibers in a visible light zone is strengthened compared with that of molybdenum trioxide powder, and the photocatalytic performance of molybdenum trioxide can be improved.

Molybdenum sulfide/multiwalled carbon nanotube hybrid material with core-shell structure, and preparation method and application of molybdenum sulfide/multiwalled carbon nanotube hybrid material

Abstract: The invention discloses a molybdenum sulfide/multiwalled carbon nanotube hybrid material with a core-shell structure, and a preparation method and application of the molybdenum sulfide/multiwalled carbon nanotube hybrid material, which belong to the technical field of the synthesis of industrial hydrogen evolution materials. The molybdenum sulfide/multiwalled carbon nanotube hybrid material with the core-shell structure is characterized in that the preparation method of the molybdenum sulfide/multiwalled carbon nanotube hybrid material with the core-shell structure comprises the following steps: dispersing a multiwalled carbon nanotube and ammonium tetrathiomolybdate in a mixed solution of N,N-dimethyl formamide and deionized water, then transferring the solution into a reaction kettle to react for 12h at 180 to 220 DEG C, centrifugally separating a reaction product, then successively washing by using ethanol and deionized water, vacuum drying the washed solid for 12 h at 100 DEG C to obtain a target product-the molybdenum sulfide/multiwalled carbon nanotube hybrid material with the core-shell structure. The molybdenum sulfide/multiwalled carbon nanotube hybrid material with the core-shell structure prepared by the invention can be well used as a hydrogen evolution catalyst and has excellent hydrogen evolution activity and stability.