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Showing papers on "Antitussive Agent published in 2020"


Journal ArticleDOI
TL;DR: Current understanding about cough pathophysiology, diagnostic strategies used to uncover underlying etiology of cough, and available options for controlling cough are reviewed, including novel antitussive therapies used in human medicine are examined.
Abstract: Cough is one of the most common complaints in human medicine. In veterinary medicine cough is equally frequent and plays a significant role in an owner's perception of their pet's quality of life. In human and veterinary medicine, therapy for chronic cough is often ineffective. The complexity of the cough pathway and species differences have made it difficult to develop an effective antitussive agent for veterinary patients. The few effective antitussive agents currently available are associated with significant adverse effects. Fortunately, several promising drugs currently being studied in human clinical trials may offer options for use of novel antitussive therapies in small animal patients. This article reviews current understanding about cough pathophysiology, diagnostic strategies used to uncover underlying etiology of cough, and examines available options for controlling cough, including novel antitussive therapies used in human medicine.

6 citations


Book ChapterDOI
01 Jan 2020
TL;DR: A recent therapeutic approach to refractory cough is reported, represented by the combination of behavioural therapy and the neuromodulator drugs.
Abstract: A wide range of disease processes may present with cough, and definitive treatment depends on identifying the cause. Specific treatment of the cause should control the cough, but this may not occur in all cases, and in a sizeable proportion of patients, no associated cause can be found. In the settings of acute cough, symptomatic treatment is often the first line of therapy. Symptomatic treatment must be also considered when the cough interferes with the patient’s daily activities; however most of antitussive preparations have not been shown to be more effective than placebo in adequately performed clinical trials. In this chapter the main antitussive drugs are examined, but for the sake of completeness, it is also discussed some other drugs often used to treat cough, though some of them are not commonly classified as antitussive agents. Finally, it is reported a recent therapeutic approach to refractory cough, represented by the combination of behavioural therapy and the neuromodulator drugs.

1 citations


Book ChapterDOI
01 Jan 2020
TL;DR: In this chapter the main antitussive drugs are examined, but for the sake of completeness, it is also discussed some other drugs often used to treat cough, though some of them are not commonly classified as antitussives agents.
Abstract: A wide range of disease processes may present with cough and definitive treatment depends on identifying the cause. Specific treatment of the cause should control the cough, but this may not occur in all cases, and in a sizeable proportion of patients, no associated cause can be found. In the settings of acute cough, symptomatic treatment is often the first line of therapy. Symptomatic treatment must be also considered when the cough interferes with the patient’s daily activities; however most of antitussive preparations have not been shown to be more effective than placebo in adequately performed clinical trials. In this chapter the main antitussive drugs are examined, but for the sake of completeness, it is also discussed some other drugs often used to treat cough, though some of them are not commonly classified as antitussive agents. Finally, it is reported recent therapeutic approach to refractory cough represented by the combination of behavioural therapy and the neuromodulator drugs.

Journal ArticleDOI
TL;DR: Husten dient der Reinigung der Bronchien und hat zunächst keinen Krankheitswert, wenn es aber zu einer Infektion der oberen Atemwege gekommen ist, könnten Entzündungsmediatoren zur Sensibilisierung der Hustenrezeptoren führen.
Abstract: Husten dient der Reinigung der Bronchien und hat zunächst keinen Krankheitswert. Wenn es aber zu einer Infektion der oberen Atemwege gekommen ist, könnten Entzündungsmediatoren zur Sensibilisierung der Hustenrezeptoren führen. Ähnliches ist von manchen Medikamenten bekannt. Worauf Sie achten müssen, wenn Ihr Patient hustet, und welche Therapiestrategie die richtige ist, erfahren Sie in diesem Beitrag.