Topic
Antitussive Agent
About: Antitussive Agent is a research topic. Over the lifetime, 380 publications have been published within this topic receiving 5776 citations.
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TL;DR: This study designed and synthesized compound 1b derivatives to improve the metabolic instability, which resulted in affording highly potent and metabolically stable oral antitussive agent.
28 citations
TL;DR: Results demonstrate antitussive activity of CP-99994 in dogs at a dose proven to antagonize tachykinin NK(1) receptors in this species.
28 citations
Patent•
04 Aug 1994
TL;DR: In this paper, the process for their preparation and the pharmaceutical compositions containing them are described, as well as the possible corresponding oxides and their possible correspondences, and the pharmacologically active tropyl 7-azaindol-3-ylcarboxamides.
Abstract: Optionally substituted pharmacologically active tropyl 7-azaindol-3-ylcarboxamides and their possible correspondent oxides, the process for their preparation and the pharmaceutical compositions containing them are described.
28 citations
TL;DR: Overall, data indicate that dimemorfan is an effective nonnarcotic antitussive agent with a low incidence of adverse events.
27 citations
Journal Article•
27 citations