Topic
Antitussive Agent
About: Antitussive Agent is a research topic. Over the lifetime, 380 publications have been published within this topic receiving 5776 citations.
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Patent•
26 Sep 1969TL;DR: The ANTITUSSIVE COMPOSITION as discussed by the authors is a competition which consists of SPECIFIC CYCLOALKENE COMPOUNDS and a PHARMACEUTICAL EXCIPIENT.
Abstract: THE ANTITUSSIVE COMPOSITION WHICH COMPRISES SPECIFIC CYCLOALKENE COMPOUNDS AND A PHARMACEUTICAL EXCIPIENT.
14 citations
01 Jan 2010
TL;DR: This review is intended to describe the current status of plant used as antitussive and expectorant and their active compounds with cough-suppressing activity.
Abstract: The problems emerging from the treatment of cough during many types of respiratory diseases by conventional opioid antitussive agents, such as codeine and codeine-like compounds. Medicinal plants are potential source of substances with high-antitussive efficiency with minimal unwanted effects. Recent trends of modern phytotherapy include specification of active substances responsible for therapeutic effect as well as their quantification in the healing drugs, which enables the treatment rationalization, especially the dosing and pursuing of adverse effects. This review is intended to describe the current status of plant used as antitussive and expectorant and their active compounds with cough-suppressing activity.
14 citations
Journal Article•
13 citations
01 Jan 2006
TL;DR: The purpose of this chapter is to give the overview of some medicinal plants and their active compounds with cough-suppressing activity, and the common information about antitussive efficiency of selected herbal products are replenished with results of the ongoing research program related to search for potentially antitussives active herbal polysaccharides.
Abstract: The problems emerging from the treatment of cough during many types of respiratory diseases by conventional opioid antitussive agents, such as codeine and codeine-like compounds, are well known. In recent years, much effort has been made to create drugs that exhibit minimum side effect on the organism. One of them is the medicinal plants, which are potential source of substances with high-antitussive efficiency with minimal unwanted effects. Recent trends of modern phytotherapy include specification of active substances responsible for therapeutic effect as well as their quantification in the healing drugs, which enables the treatment rationalization, especially the dosing and pursuing of adverse effects. The purpose of this chapter is to give the overview of some medicinal plants and their active compounds with cough-suppressing activity. The common information about antitussive efficiency of selected herbal products are replenished with results of our ongoing research program related to search for potentially antitussive active herbal polysaccharides.
13 citations
TL;DR: The cough reflex was stimulated in selected healthy male subjects with a single nebulized threshold dose of citric acid and a dose‐response curve was obtained for codeine and dextromethorphan.
Abstract: The cough reflex was stimulated in selected healthy male subjects with a single nebulized threshold dose of citric acid. The essential components of the method were deep inhalation by the subjects and the measurement of the required time to elicit the cough reflex. Prolongation of latency was used as a measure of antitussive action. With the use of this parameter, a dose‐response curve was obtained for codeine and dextromethorphan.
13 citations