Topic
Antitussive Agent
About: Antitussive Agent is a research topic. Over the lifetime, 380 publications have been published within this topic receiving 5776 citations.
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TL;DR: In this article, the authors investigated the effect of RU-20201 on dogs and guinea pigs with puncture electrode-induced cough (PEC) and chemical stimulation methods, respectively.
Patent•
03 Dec 1982
TL;DR: In this paper, the acid-addn. salts are new (where Ar is tetrahydro-naphthyl, naphthyclic, 4-Ar'-phenyl or 4Ar'-benzyl; Ar' is phenyl or halophenyl).
Abstract: N-(2-pyrrolidino-ethyl) carboxamides of formula (I) and their acid-addn. salts are new (where Ar is tetrahydro-naphthyl, naphthyl, 4-Ar'-phenyl or 4-Ar'-benzyl; Ar' is phenyl or halophenyl). Specifically claimed are (I) where Ar is p-biphenylyl, 1,2,3,4-tetrahydro -2-naphthyl, p-(o-chlorophenyl) phenyl, p-phenylbenzyl, p-(o-chlorophenyl) benzyl and 1-naphthyl. (I) are antitussive agents with a less bitter taste than the related cpds. of FR 7507799.
01 Jan 1986
TL;DR: The drug has been characterized pharmacologically and clinically in humans as an analgesic and as a component of balanced anaesthesia, and in dogs it has been used as an antitussive agent.
Abstract: Butorphanol is a synthetic opiate of the cyclorphan series which possesses both narcotic agonist and antagonist properties. The drug has been characterized pharmacologically and clinically in humans as an analgesic and as a component of balanced anaesthesia, and in dogs it has been used as an antitussive agent.