Aquation

About: Aquation is a research topic. Over the lifetime, 1443 publications have been published within this topic receiving 17507 citations.

Synthesis and characterization of (bipyridine)(terpyridine)(chalcogenoether)ruthenium(II) complexes. Kinetics and mechanism of the hydrogen peroxide oxidation of [(bpy)(tpy)RuS(CH3)2]2+ to [(bpy)(tpy)RuS(O)(CH3)2]2+. Kinetics of the aquation of [(bpy)(tpy)RuS(O)(CH3)2]2+

Abstract: Preparation des complexes de formule generale [(bpy)(tpy)Ru II L] 2+ . Cinetique de l'oxydation par H 2 O 2 et de l'aquation (vitesse independante de [H + ])

Mechanistic Information on the Aquations of Complexes of the Pentaamminecobalt(III) Series from Kinetic Studies at High Pressures

Abstract: The logarithm of the pseudo-first-order rate coefficient k for the aquation of Co(NH3)5X(3–n)+ can be represented by a quadratic equation in the pressure P, or, better, bywhere P is in kbar, is the...

Kinetic investigation of the DNA platination reaction: evidence for a transient adduct between deoxyribonucleic acid and cis-platinum(II).

Abstract: Kinetics of the synthesis of adducts between salmon testis DNA and platinum(II) compounds were measured by their effects on DNA synthesis, circular dichroism, and ethidium bromide dependent fluorescence. Transient incorporation of (/sup 14/C)cyanide into DNA adducts of cis-diammineaquochloroplatinum(II) and respectively cis-diamminediaquoplatinum(II) compounds but not of trans-diammineaquochloroplatinum(II) was observed. A minimal kinetic scheme is derived, in which a transient monodentate DNA-platinum(II) adduct is formed in a bimolecular reaction between DNA and aquated platinum(II) compounds. The dependence of pseudo-first-order rate constants is not linear for high concentrations of DNA, suggesting competitive formation of more than one primary adduct. The monodentate adducts inhibit DNA polymerase catalyzed DNA synthesis. The bimolecular reaction is followed by a rearrangement (rate constant 0.22 min/sup -1/) that gives rise to most of the decrease in the fluorescence intensity and that depends on the state of aquation of the DNA-bound platinum(II) complex. By exchange of coordinated water with a second nucleotide, the monodentate adduct can form cross-links in a reaction joining the rearrangement. Adducts containing a chloro group liberate it by hydrolysis prior to cross-linking. In the case of the trans-platinum(II) adduct, the hydrolysis is aided by the trans effect of the bound first nucleotide. The reaction sequence ismore » concluded by a final rearrangement that gives rise to characteristic changes in the spectra of circular dichroism. cis- and trans-platinum(II)-DNA adducts depart from a common reaction path after formation of the monodentate adduct.« less