Arabitol

About: Arabitol is a research topic. Over the lifetime, 388 publications have been published within this topic receiving 8398 citations. The topic is also known as: D-(+)-Arabitol & D-arabitol.

METHOD FOR STABILIZING p-HYDROXYBENZOATE HYDROXYLASE

Abstract: PROBLEM TO BE SOLVED: To improve the storage stability of p-hydroxybenzoate hydroxylase and to enable long-term stability of enzyme product by selecting a stabilizer. SOLUTION: The method for stabilizing p-hydroxybenzoate hydroxylase comprises the addition of at least one kind of α-cyclodextrin, inositol, sucrose, sorbitose, citric acid, sodium gluconate, BSA, arabitol and trisodium EDTA as a stabilizer. COPYRIGHT: (C)2008,JPO&INPIT

Biotechnological production of sugar-alcohols: focus on Yarrowia lipolytica and edible/medicinal mushrooms

Abstract: In the present review-article several aspects dealing with the biotechnological production of three major sugar-alcohols, viz. erythritol, mannitol and arabitol, are developed. Emphasis is given on the extra-cellular production of these sugar-alcohols by species of the yeast cell factory Yarrowia lipolytica and/or their intra-cellular accumulation in genera/species (mostly Agaricus and Pleurotus) of edible and medicinal mushrooms. Indications concerning the presence of soluble sugars inside the fungal mycelia and fruit-bodies of various types of mushrooms are also added. Initially, general information concerning the mentioned sugar-alcohols as well as others that are produced by biotechnological means, their roles, and their functionalities, are presented. The biochemistry of the synthesis of erythritol, mannitol and arabitol in the yeast cells and fungal mycelia when the main carbon sources employed in the Industrial Biotechnology (viz. glucose/fructose, lignocellulosic compounds/xylose, hydrophobic materials, glycerol) are used is presented and critically discussed. Given that the yeast Y. lipolytica is a major candidate that has been/is implicated in the production of the mentioned sugar-alcohols together with other compounds that are synthesized through similar metabolic pathways (viz. microbial lipids and citric acid, produced as the mentioned polyols during the imbalanced growth phase and after carbon-excess and nitrogen-limited conditions) various considerations concerning the biotechnological potential of this yeast species with emphasis of the production of sugar-alcohols are developed and assessed. Finally, presentations concerning the production of sugar-alcohols and other soluble sugars through the cultivation of various types of edible/medicinal mushrooms in several types of fermentation configurations are critically assessed.

Xylitol dehydrogenase-inactivated and arabinose reductase-inhibited mutant of Candida tropicalis, method of producing high-yield of xylitol using the same, and xylitol produced thereby

Abstract: Disclosed herein are Xylitol dehydrogenase-inactivated and arabinose reductase-inhibited mutant of Candida tropicalis, a method of producing a high yield of xylitol using the same, and xylitol produced by the method. More specifically, disclosed are a method for producing a high yield of xylitol, in which a high concentration of xylose contained in a biomass hydrolyzate is converted to xylitol using xylitol dehydrogenase-inactivated mutant of Candida tropicalis, without controlling dissolved oxygen to a low level, as well as xylitol produced according to the method. Also disclosed are a xylitol production method, in which the production of byproduct arabitol, which is produced when using a biomass as a substrate and adversely affects the yield of xylitol, is significantly reduced through the use of Candida tropicalis mutant ara-89 (KCTC 11136bp) having an inhibited activity of arabinose reductase converting arabinose to arabitol, thus increasing xylitol productivity, as well as xylitol produced by the method.

L-Arabitol and Ribitol Production by a Corynebacterium Species

Abstract: Aldopentose reductases of a Corynebacterium species were investigated.Chromatography of cell-free extracts from this bacterium on Sephadex G–100 revealed the presence of two distinct enzyme fractions with reducing activity on aldopentoses.The elution pattern of the two enzyme fractions obtained from cells grown in a gluconate-l-arabinose medium was the same as that from cells grown in a gluconate-d-ribose medium.The first fraction (Reductase I) showed considerably high activity on d-ribose, and the second fraction (Reductase II), on both l-arabinose and d-xylose.The reduction of l-arabinose to l-arabitol and of d-ribose to ribitol was demonstrated by the coupling reaction of the reductase and phosphogluconate dehydrogenase with NADP as a cofactor.