Aromatic hydrocarbon

About: Aromatic hydrocarbon is a research topic. Over the lifetime, 5814 publications have been published within this topic receiving 55499 citations. The topic is also known as: arene & arenes.

The bay-region theory: a quantum mechanical approach to aromatic hydrocarbon-induced carcinogenicity

Abstract: Publisher Summary This chapter presents the bay-region theory as a quantum mechanical approach to aromatic hydrocarbon-induced carcinogenicity. The bay-region theory is a prediction both of biological activity and chemical reactivity. Recent studies have been designed to test the theory for the hydrocarbon benzo[a]anthracene. In an experiment described in the chapter, five metabolically possible trans-dihydrodiols of the hydrocarbon were synthesized to examine the ability of a highly purified and reconstituted cytochrome P-448 system to metabolize them to compounds mutagenic toward bacteria. As a substrate for the formation of mutagens, the 3,4-dihydrodiol was found to be 10 times more active than the other dihydrodiols or the parent hydrocarbons. Because the 3,4-dihydrodiol can form bay-region epoxides at the 1,2-position, which were predicted to be the most reactive, the quantum mechanical predictions are borne out. Similar support for the bay-region concept has been found through metabolic activation of dihydrodiols from benzo[a]-pyrene. As anticipated, dihydrodiols from smaller hydrocarbons such as naphthalene, anthracene, or phenanthrene could not be activated to produce significant numbers of mutations.

Novel complex and preparing method thereof and organic electroluminescent device using them

Abstract: PURPOSE: A process for preparing a novel complex compound having a band gap corresponding to a blue colour and a high melting point and an organic electroluminescent device are provided which improve thermal stability when applied to electroluminescent devices. CONSTITUTION: An organic metal complex represented by the general formula 1, an organic electric field electroluminescent device comprising a layer containing the complex between the positive and negative poles and processes for preparing thereof are described. In formula, R1,R2,R3 are each independently or simultaneously substituents selected from the group consisting of H, lower hydrocarbon, halogen, alkoxy, arylamine, nitro, nitryl, aldehyde, ester, sulfurous hydrocarbon(-SR), aromatic hydrocarbon, and C1-12 hetero ring compounds; ring A is a ring compound selected from the group consisting of an aromatic comprising a nitrogen atom of an imidazole group and an adjacent carbon atom, an aromatic containing C5-12 hetero ring and C4-11 hetero ring containing N-R4 (R4 is a substituent selected from the group consisting of H, lower hydrocarbon, saturated aliphatic hydrocarbon, and aromatic ring compound; the ring B is a ring compound selected from an aromatic which combines with a carbon atom of an imidazole group or a C5-12 hetero ring; M is a metal selected from the group consisting of beryllium, zinc, magnesium, aluminium, gallium, and indium; n is an integer from 2 to 3.