Topic
Artocarpus
About: Artocarpus is a research topic. Over the lifetime, 813 publications have been published within this topic receiving 9810 citations.
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TL;DR: In the present review, attempts on the important findings have been made on identification; synthesis and bioactivity of metabolites present in Artocarpus which have been highlighted along with the current trends in research on Artoc carpus.
260 citations
Journal Article•
TL;DR: The results of the work clearly indicate the potential of these extracts to manage hyperglycemia and screen novel alpha amylase and alpha glucosidase inhibitors from natural sources like plants in order to minimize the toxicity and side effects of the inhibitors currently used to control hyperglycaemia.
Abstract: The aim of this work was to evaluate the inhibitory activities of methanolic extracts of Artocarpus altilis,
Cinnamomum zeylanicum, Piper betel and Artocarpus heterophyllus on Wheat alpha amylase and Baker’s yeast
alpha glucosidase at varying concentrations. Diabetes mellitus is a clinical condition characterized by
hyperglycaemia in which an elevated amount of glucose circulates in the blood plasma. Alpha amylase and alpha
glucosidase inhibitors are used to achieve greater control over hyperglycemia in type 2 diabetes mellitus. The
present study intends to screen novel alpha amylase and alpha glucosidase inhibitors from natural sources like
plants in order to minimize the toxicity and side effects of the inhibitors currently used to control hyperglycemia.
The alpha amylase inhibition assay showed that the methanolic extracts of Cinnamomum zeylanicum (130.55
μg/mL), Artocarpus altilis (118.88 μg/mL), Piper betel (84.63 μg/mL) and Artocarpus heterophyllus (70.58 μg/mL)
exhibited 50% alpha amylase inhibition activity at the mentioned concentrations. The alpha glucosidase IC50 for the
plant extracts A. altilis, A. heterophyllus, C. zeylanicum and Piper betel was found to be 129.85±10.29, 76.90±9.55,
140.01±10.08 and 96.56±12.93 μg/ml respectively. The results of the work therefore clearly indicate the potential of
these extracts to manage hyperglycemia.
195 citations
TL;DR: A review of the nutritional value, culinary uses, phytochemical compounds, traditional usage and validated pharmacological properties of the jackfruit tree is presented in this article, where the authors have shown that the decoction of the leaves possesses hypoglycemic effects in both healthy individuals and non-insulin-dependent diabetic patients.
168 citations
01 Jan 2011
TL;DR: In this article, the screening and study of seven different plant specimens belonging to different families for phytochemical constituents was performed using generally accepted laboratory technique for qualitative determinations, and the constituents screened for were tannins, saponins, phlobotannin, terpenoids, flavonoids, cardiac glycosides, combined anthraquinone, free-anthraquinones, carotenoids, steroids, reducing compounds and alkaloids.
Abstract: The screening and study of seven different plant specimens belonging to different families for phytochemical constituents was performed using generally accepted laboratory technique for qualitative determinations. The constituents screened for were tannins, saponins, phlobotannins, terpenoids, flavonoids, cardiac glycosides, combined anthraquinone, free-anthraquinone, carotenoids, steroids, reducing compounds and alkaloids. The distribution of these constituents in the plant specimens were assessed and compared. The plant seeds studied were Artocarpus communis, Artocarpus heterophyllus, Calophyllum inophyllum, Garcinia kola, Garcinia mangostana, Pentaclethra macrophylla and Treculia africana. All the plant specimens were found to contain flavonoids and reducing compounds but none of them contain phlobatanin, cardiac glycoside, combined anthraquinone, free anthraquinone, carotenoid and steroids. They also contain tannins (except Artocarpus communis), saponins (except Artocarpus heterophyllus) and terpenoids (except Artocarpus communis). Alkaloids were found in four out the seven specimens. Some of the plant seeds seemed to have potential as source of useful drugs.
159 citations
TL;DR: Two isoprenylated 2-arylbenzofurans, artoindonesianins X and Y (1-2), together with seven known flavonoids, have been isolated from the roots and tree bark of Artocarpus fretessi on the basis of spectral analysis.
150 citations