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Showing papers on "Bacillus anthracis published in 1975"


Journal ArticleDOI
TL;DR: The characteristic hemorrhagic features in two patients who died despite antibiotic treatment are presented and discussed and the mechanism behind the deaths is discussed.
Abstract: Bacillus anthracis is an uncommon cause of meniningitis. The characteristic hemorrhagic features in two patients who died despite antibiotic treatment are presented and discussed.

36 citations


Journal ArticleDOI
TL;DR: The fine structure of γ phage of Bacillus anthracis was studied by electron microscopy with a negative-staining technique and the phage has a hexagonal head and a long tail without a sheath.
Abstract: The fine structure of γ phage of Bacillus anthracis was studied by electron microscopy with a negative-staining technique. The phage has a hexagonal head and a long tail without a sheath. By electrophoresis on polyacrylamide gels, the proteins of the phage particles are separate into 10 polypeptides with moleclar weights ranging from 140 000 to 12 000.

24 citations


Journal ArticleDOI
TL;DR: Results suggest the possibility that one or a combination of these substances defines the characteristics of phage adsorption to the cell walls of B. anthracis, strain Pasteur No. 2-H.
Abstract: Cell wall preparations of Bacillus anthracis, strain Pasteur No. 2-H, were treated with heat or with acetone and ether. Both of the treated cell walls preparations inactivated gamma phage. The centrifuged supernatant of the heat-treated cell walls was fractionated on Sephadex G-200, and four fractions containing reducing sugars were obtained. The first fraction had the phage-inactivating activity. On the other hand, the fourth fraction had no phage-inactivating activity, but strongly inhibited phage adsorption to the cell walls. In the fourth fraction, glutamic acid, alanine, 2,6-diaminopimelic acid and glucosamine were detected by paper chromatography after acid hydrolysis. Authentic D, L-2, 6-diaminopimelic acid and D-glucosamine markedly inhibited phage adsorption to the cell walls. D-Galactosamine, D-mannosamine and L-lysine also showed similar activities. Results suggest the possibility that one or a combination of these substances defines the characteristics of phage adsorption to the cell walls of B. anthracis, strain Pasteur No. 2-H.

8 citations


Journal ArticleDOI
TL;DR: The morphological changes occurring in the regional lymph nodes and the parenchymal organs of the experimental animals under the influence of the protective antigen of Bacillus anthracis have been elucidated.