Topic
Benzopyran
About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.
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TL;DR: Synthesis and physico-chemical properties of two 3-substituted phenacyl-thiazolidine-2,4-diones (2c-d) and four 3- substituting phenacy l-5-[2-phenyl-4H-4-oxo-1-benzopyran-6-yl)methyl-enyl]- thiazolidin e- 2, 4- diones are described.
Abstract: Synthesis and physico-chemical properties of two 3-substituted phenacyl-thiazolidine-2,4-di-ones (2c-d) and four 3-substituted phenacyl-5-[2-phenyl-4H-4-oxo-1-benzopyran-6-yl)methyl-enyl]-thiazolidine-2.4-diones (4a-d) are described. These products were synthesized by Knoevenagel reaction from flavone-6-carboxaldehydc (3) and 3-(substituted phenacyl)-thiazolidine-2,4-diones (2a-d). Antibacterial and antifungal activities were investigated for these compounds.
7 citations
7 citations
Patent•
24 Apr 1992TL;DR: A benzopyran derivative represented by general formula (I) and a pharmaceutically acceptable salt thereof, wherein each symbol is as defined in the specification, is useful for treating hypertension, because it has a persistent hypotensive activity and a peripheral blood relaxing activity by activating a potassium channel, and also for treating cardiovascular diseases such as angina pectoris and heart failure as discussed by the authors.
Abstract: A novel benzopyran derivative represented by general formula (I) and a pharmaceutically acceptable salt thereof, wherein each symbol is as defined in the specification. This compound is useful for treating hypertension, because it has a persistent hypotensive activity and a peripheral blood relaxing activity by activating a potassium channel, and also for treating cardiovascular diseases such as angina pectoris and heart failure, because it has a selective coronary blood stream increasing activity.
7 citations
TL;DR: In this paper, the stereochemical correlations including the configurations of the ring juncture and the methyl group and also the ring conformations of these six lactones were investigated by chemical means and by nuclear magnetic resonance (NMR) spectrometry, such as two-dimensional(2D) NMR and steady-state 1H-1H nuclear Overhauser effect experiments.
Abstract: Four stereoisomers of 3-methyloctahydroisocoumarins (4a-d)and two 1-methyloctahydro-3H-2-benzopyran-3-ones (10a, b) were synthesized. The stereochemical correlations including the configurations of the ring juncture and the methyl group and also the ring conformations of these six lactones were investigated by chemical means and by nuclear magnetic resonance (NMR) spectrometry, such as two-dimensional(2D) NMR and steady-state 1H-1H nuclear Overhauser effect experiments. It was concluded that the lactone ring of 4b, c, and 10a adopts a boat or a slightly distorted boat conformation in solution.
7 citations
TL;DR: The photochromism of [7-hydroxy-8-formyl-3-methyl-4-oxospiro[1,3-benzoxazin-2,2 ǫ]-[2H-1]benzopyran],SP(I),SP(II) and their coordination with Tb3.
Abstract: The photochromism of [7-hydroxy-8-formyl-3-methyl-4-oxospiro[1,3-benzoxazin-2,2-[2H-1]benzopyran],SP(I),[7-hydroxy-8-formyl-3-benzyl-4-oxospiro[1,3-benzoxazin-2,2-[2H-1]benzopyran] SP(II) and their coordination with Tb3
7 citations