Topic
Benzopyran
About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.
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TL;DR: A copper(I)bromide promoted substitution of 2-bromobenzofuran-3-carboxylic acid (2b) with dimedone and subsequent lactonization offers a new route to a modified coumestane ring system.
4 citations
Patent•
02 Aug 1979TL;DR: In this article, 7-[3-(4-Acetyl-3-hydroxy-6-iodo-2-propylphenoxy)-2-hydroxypyran-2 carboxylic acid and its pharmaceutically acceptable salts are employed as antagonists of SRS-A (slow reacting substance of anaphylaxis) in the treatment of asthma and allergic diseases.
Abstract: 7-[3-(4-Acetyl-3-hydroxy-6-iodo-2-propylphenoxy)-2-hydroxypropoxy]-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid and its pharmaceutically acceptable salts are employed as antagonists of SRS-A (the slow reacting substance of anaphylaxis) in the treatment of asthma and allergic diseases.
4 citations
TL;DR: Salicylidenes prepared from 5-ethyl-4-thiolen-2-one undergo base-catalyzed rearrangement to 4H-thieno[3,2-c][1]benzopyran-4.
4 citations
TL;DR: In this paper, Nitroalkenes bearing an additional -CF3 function react with 2-hydroxychalcones in the presence of the cinchona alkaloid CASQ to produce the desired functionalized benzopyran structures in a completely stereoselective manner.
Abstract: Nitroalkenes bearing an additional -CF3 function react with 2-hydroxychalcones in the presence of the cinchona alkaloid CASQ to produce the desired functionalized benzopyran structures in a completely stereoselective manner.
4 citations
Patent•
03 Apr 2013
TL;DR: In this article, a method for the synthesis of a benzopyran chiral compound is described. But the method is not suitable for large-scale production and application, and it requires high yield and high optical purity.
Abstract: The invention discloses a synthetic method of a benzopyran chiral compound. The method comprises the following steps: a compound with the structural formula I and a compound with the structural formula II carry out the condensation reaction to generate a compound with the structural formula III, and the compound with the structural formula III is oxidized to obtain the benzopyran chiral compound; the chemical additive adopts a benzoic acid or a substituted benzoic acid compound; and the chiral catalyst is a diphenyl prolinol ester compound or dinaphthyl prolinol ester compound. The synthetic method has the advantages that under the mild condition, relatively cheap raw materials are used, the benzopyran chiral compound derivate is synthesized with high yield, and the derivate is high in optical purity, accessible in raw material, and beneficial for large-scale production and application.
4 citations