Topic
Benzopyran
About: Benzopyran is a research topic. Over the lifetime, 1889 publications have been published within this topic receiving 15235 citations.
Papers published on a yearly basis
Papers
More filters
TL;DR: A new and efficient synthetic approach for biologically interesting natural mallotophilippens C and E is described and the key strategies involved ethylenediamine diacetate-catalyzed benzopyran formation reactions and base-Catalyzed aldol reactions.
Abstract: This paper describes a new and efficient synthetic approach for biologically interesting natural mallotophilippens C and E. The key strategies involved ethylenediamine diacetate-catalyzed benzopyran formation reactions and base-catalyzed aldol reactions.
43 citations
TL;DR: The chemistry and application of the title aldehyde and some simple derivatives thereof are reviewed in this paper, where the authors propose a simple derivative of the aldehydes, which they call simple aldeheeds.
42 citations
TL;DR: A short stereoselective synthesis of (3R)-3,4-dihydro-6,8-dimethoxy-3-undecyl-1H-[2]benzopyran-1-one and derivatives isolated from Ononis natrix has been described as discussed by the authors.
Abstract: A short stereoselective synthesis of (3R)-3,4-dihydro-6,8-dimethoxy-3-undecyl-1H-[2]benzopyran-1-one and derivatives isolated from Ononis natrix has been described. Condensation of dodecanoyl chloride with 3,5-dimethoxyhomophthalic acid afforded 6,8-dimethoxy-3-undecylisocoumarin 3, which, on sequential saponification and esterification, yielded the keto ester 5. Enantioselective reduction of 5 with TarB-NO2/LiBH4 directly furnished the title dihydroisocoumarin 1a in 80% ee (82% yield). Partial as well as complete demethylation of the latter provided the dihydroisocoumarins 1b and 1c, respectively. Diastereotopy of the CH2 H-atoms on either side of the stereogenic center (C(3)) and the mass-fragmentation pattern of the dihydroisocoumarins have also been described. All of the compounds synthesized were examined in vitro for antifungal activity.
42 citations
TL;DR: An efficient and convenient method for the synthesis of fused pyran rings via intramolecular palladium-catalysed cyclisation followed by β-H elimination or C-H activation has been developed as discussed by the authors.
42 citations
TL;DR: K-10 Montmorillonite mediated condensation of aldehyde 1 with arylamine 2 affords chroman-2,4-dione 5 which gives tricoumarol 8 by acid hydrolysis, 4-arylamino-3-formylcoumarin 11 and 1-benzopyrano[4,3-b]quinoline 12 on heating with POCl3 as discussed by the authors.
41 citations